In this free webinar, the featured speakers will explain how the TME with multiplex immunohistochemistry is crucial for deciphering drug mechanisms of action on immune cells. Attendees will learn about the type of meaningful data that is obtained on pre- and post-treated patient samples.
TORONTO (PRWEB) June 02, 2020
Join Nagy Habib, Professor of Surgery, Imperial College London; Co-Founder, MiNA Therapeutics and Jacques Fieschi, PhD, VP of R&D, HalioDx in a live webinar on Monday, June 8, 2020 at 11am EDT (4pm BST/UK).
Assessing the tumor microenvironment has proved to be immensely informative in the context of clinical trials. Multiplex immunohistochemistry is the best suitable technology, allowing spatial detection and quantification of complex immune cell phenotypes.
Thanks to the unique HalioDx’ Brightplex® technology, pharma companies can access customized panels, providing valuable data and insights to further understand the mechanism of action of their drugs.
MTL-CEBPA is a small activating RNA therapeutic (saRNA) which, when combined with sorafenib, induces a novel myeloid differentiation in patients with advanced hepatocellular carcinoma (HCC).
HalioDx has specifically developed 3 Brightplex® panels, containing up to seven biomarkers each, for the identification and the quantification of different myeloid cells such as myeloid derived suppressor cells (MDSCs), neutrophils (N1/N2) and M1 and M2 macrophages on treated patient samples.
This technology, which uses one FFPE slide per panel, was rolled out to explore these changes by comparing pre- and post-treated samples from patients who have received MTL-CEBPA in combination with sorafenib during a Phase I a/b of a clinical trial study.
For more information or to register for this event, visit Exploring Changes of Myeloid Cells with Chromogenic Multiplex IHC in Advanced Liver Cancer.
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For the original version on PRWeb visit: https://www.prweb.com/releases/exploring_changes_of_myeloid_cells_with_chromogenic_multiplex_ihc_in_advanced_liver_cancer_upcoming_webinar_hosted_by_xtalks/prweb17161087.htm