The markets opened higher with the Dow climbing 91 points to 19,823 on inauguration day. Nasdaq gained 28 points to 5,568.

On the upside

Interspace Diagnostics (Nasdaq: IDXG) entered an agreement with Best Med Opinion for Best Med to provide physicians and patients with information regarding Interspace Diagnostics' ThyGenX, ThyraMir and PancraGen tests.

Skyworks Solutions (Nasdaq: SWKS) reported better than expected earnings for the first quarter and announced a $500 million stock repurchase plan.

Bargain hunters lifted shares of EnteroMedics (Nasdaq: ETRM).

On the downside

Pluristem (Nasdaq: PSTI) increased its previously announced bought deal to $15 million.

Bristol-Myers (NYSE: BMY) will not pursue accelerated approval for its lung cancer treatment Opdivo.

Afirmed (Nasdaq: AFMD) priced its public offering of 10 million shares of common stock at the discounted price of $1.80 per share.

In the broad market, advancing issues outpaced decliners by a margin of nearly 5 to 2 on the NYSE and by more than 5 to 3 on Nasdaq. The broader S&P 500 index climbed 11 points to 2,274. Bitcoin added $3 to $891.