The markets closed flat on a slow trading day with the Dow adding 11 points to 19,945. Nasdaq gained 24 points to 5,504.

On the upside

Analysts recently reiterated their Buy ratings on Conatus Pharmaceuticals (Nasdaq: CNAT).

Shares of Cyclacel Pharmaceuticals (Nasdaq: CYCC) surged on no news.

Moleculin Biotech (Nasdaq: MBRX) stock soared on no news.

On the downside

Investors locked in profits on Portola Pharmaceuticals (Nasdaq: PTLA).

The Food and Drug Administration issued a Complete Response Letter to Amphastar Pharmaceuticals (Nasdaq: AMPH) for its New Drug Application for Primatene Mist.

Stone Energy (NYSE: SGY) stock fell for the third day.

In the broad market, advancing issues outpaced decliners by a margin of nearly 5 to 3 on the NYSE and by nearly 7 to 5 on Nasdaq. The broader S&P 500 index gained 5 points to 2,268. Bitcoin surged $35 to $919.