The European Central Bank’s weak stimulus measures sent the markets tumbling during the midday with the Dow plunging 136 points to 17,593. Nasdaq plummeted 61 points to 5,061.

On the upside

Shares of Truett-Hurst (Nasdaq: THST) continued climbing after suing its landlord.

FBR Capital initiated coverage of Prima BioMed (Nasdaq: PBMD) with an Outperform rating and a $6 price target.

Bargain hunters lifted shares of Rex Energy (Nasdaq: REXX).

On the downside

Box (NYSE: BOX) widened losses for the third quarter.

Disappointment with the European Central Bank’s weak stimulus measures weighed down shares of exchange-traded funds operator WisdomTree Investments (Nasdaq: WETF).

Profit taking continued to sink shares of Giga-tronics (Nasdaq: GIGA).

In the broad market, advancing issues outpaced decliners by a margin of more than 5 to 2 on the NYSE and by more than 5 to 3 on Nasdaq. The broader S&P 500 tumbled 17 points to 2,061. Bitcoin rose $3 to $361.