It was a mixed close for the markets with the Dow gaining 52 points to 12,150 as European leaders considered a second bailout fund to contain the debt crisis. Nasdaq slipped 6 points to 2649.

On the upside

Clearwire (Nasdaq: CLWR) will raise approximately $595 million through a stock offering.  

Cell Therapeutics’ (Nasdaq: CTIC) resubmitted new drug application for non-Hodgkin’s lymphoma treatment pixantrone was considered complete by the Food and Drug Administration. 

The Benchmark Company upgraded Orbitz Worldwide (NYSE: OWW) to a Hold rating.

On the downside

Investors locked in profits on Affymax (Nasdaq: AFFY), whose stock price climbed yesterday after the Food and Drug Administration determined that the company’s anemia treatment was just as effective as Amgen’s (Nasdaq: AMGN) Epogen. 

Credit Suisse analyst Edward Westlake downgraded Tesoro (NYSE: TSO) to a Neutral rating. 

The lock-up period for Fusion-io (NYSE: FIO) expired today.

In the broad market, advancing issues barely edged out decliners by a slim margin of nearly 10 to 9 on the NYSE while decliners outpaced advancers by 9 to 7 on Nasdaq. The Russell 2000 which tracks small cap stocks eased a fraction to 746.