The markets closed mixed with the Dow plunging 141 points to 17,672 over disappointing home sales data. Nasdaq added 7 points to 4,757.

On the upside

The Food and Drug Administration approved Nevro’s (NYSE: NVRO) Senza spinal cord stimulation system.

Bargain hunters lifted shares of Eagle Pharmaceuticals (Nasdaq: EGRX).

Otonomy (Nasdaq: OTIC) priced its follow-on pubic offering of 2.55 million common shares at $29.25 per share.

On the downside

Goldman Sachs cut its 2015 iron ore forecast sending shares of Cliffs Natural Resources (NYSE: CLF) tumbling.

Shares of Alpha Natural Resources (NYSE: ANR) fell after Standard & Poor’s said that coal prices would remain depressed this year.

Shares of Alamos Gold (NYSE: AGI) extended its losses.

In the broad market, declining issues outpaced advancers by a margin of 5 to 4 on the NYSE and on Nasdaq. The broader S&P 500 dropped 11 points to 2051. Bitcoin added $3 to $232.