Celldex Therapeutics, Inc. (NASDAQ: CLDX) will review data on Monday, November 22, 2010 from the rindopepimut (CDX-110) ACT III study that will be presented at the Annual Scientific Meeting of The Society for Neuro-Oncology (SNO) in Montreal, Quebec, Canada. Celldex executives will host a conference call at 8:30 am Eastern Time. Rose Lai, M.D., Assistant Professor of Neurology in the Division of Neuro-Oncology, Department of Neurology, Columbia University Medical Center, will join the call. Dr. Lai is a leading investigator in the ACT III, Phase 2 study of rindopepimut in patients with newly diagnosed glioblastoma multiforme (GBM).

The conference call and presentation will be webcast live over the Internet and can be accessed by logging on to the “Presentations” page of the “Investors” section of the Celldex website at www.celldextherapeutics.com. The call can also be accessed by dialing 866-730-5770 (within the United States) or 857-350-1594 (outside the United States). The passcode for participants is 76849635.

A replay of the call will be available approximately two hours after the live call concludes through December 5, 2010. To access the replay, dial 888-286-8010 (within the United States) or 617-801-6888 (outside the United States). The passcode is 70523463. The webcast will also be archived on the Company’s website.

About Celldex Therapeutics, Inc.

Celldex Therapeutics is the first antibody-based combination immunotherapy company. Celldex has a pipeline of drug candidates in development for the treatment of cancer and other difficult-to-treat diseases based on its antibody focused Precision Targeted Immunotherapy Platform. The PTI Platform is a complementary portfolio of monoclonal antibodies, antibody-targeted vaccines and immunomodulators used in optimal combinations to create novel disease-specific drug candidates. For more information, please visit http://www.celldextherapeutics.com.