“Aclarion uses MR spectroscopy to analyze the physiological status of lumbar intervertebral discs. Being able to quantify the chemical biomarkers content of discs in chronic low back pain patients adds an entirely new dimension of clinically relevant information that anatomical imaging alone simply can't provide,” said Dr. Simon Blease, Consultant Musculoskeletal Radiologist. “Having progressed through a careful integration of Nociscan into patient care pathways, we have found compelling results in over 20 patients so far. We are convinced this will be a game changer for how we will evaluate and plan treatment for this common and distressing clinical condition."

The initial contract with The London Clinic was aimed at allowing The London Clinic physicians to evaluate the clinical value of Nociscan in treating their chronic low back pain patients. After utilizing Nociscan in just 20 patients, the physicians saw enough value to support a contract extension aimed at increasing access to Nociscan for patients. Increased access is being pursued through outreach to referring physicians, increasing the reimbursement to Aclarion, and approaching the payer community to secure private insurance coverage for Nociscan.

“The UK is an important global market, and London specifically represents the large, dynamic nature of sophisticated healthcare,” said Brent Ness, Chief Executive Officer at Aclarion.  “We are pleased to extend our relationship with The London Clinic as the Nociscan hub throughout greater London, a market with over nine million residents. The London Clinic and their referring physicians have become exemplary partners delivering world-class spine care while serving as validation of our process to drive Nociscan to standard of care. We started with an initial evaluation contract for physicians to become familiar with the unprecedented biomarker data Nociscan provides and how to apply that data for surgical decisioning. After only 20 patients The London Clinic took the initiative in extending the contract by increasing the payment rate for Nociscan, advocating with payers for coverage, and working with Aclarion to expand access to referring physicians. This is the exact process we are pursuing with our KOLs across the U.S. at similarly prestigious institutions and we believe we will achieve similar results.”

Chronic low back pain (cLBP) is a global healthcare problem with approximately 266 million people worldwide suffering from degenerative spine disease and low back pain. Low back pain has been estimated to affect up to one third of the UK adult population each year.

For more information about The London Clinic, please visit: www.thelondonclinic.co.uk

For more information about the London Spine Clinic, please visit: www.londonspineclinic.com

About Aclarion, Inc.

Aclarion is a healthcare technology company that leverages Magnetic Resonance Spectroscopy (“MRS”), proprietary signal processing techniques, biomarkers, and augmented intelligence algorithms to optimize clinical treatments. The Company is first addressing the chronic low back pain market with Nociscan, the first, evidence-supported, SaaS platform to noninvasively help physicians distinguish between painful and nonpainful discs in the lumbar spine. Through a cloud connection, Nociscan receives magnetic resonance spectroscopy (MRS) data from an MRI machine for each lumbar disc being evaluated. In the cloud, proprietary signal processing techniques extract and quantify chemical biomarkers demonstrated to be associated with disc pain. Biomarker data is entered into proprietary algorithms to indicate if a disc may be a source of pain. When used with other diagnostic tools, Nociscan provides critical insights into the location of a patient’s low back pain, giving physicians clarity to optimize treatment strategies.  For more information, please visit www.aclarion.com.

Forward Looking Statements

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 about the Company's current expectations about future results, performance, prospects and opportunities. Statements that are not historical facts, such as "anticipates," "believes" and "expects" or similar expressions, are forward-looking statements. These forward-looking statements are based on the current plans and expectations of management and are subject to a number of uncertainties and risks that could significantly affect the Company's current plans and expectations, as well as future results of operations and financial condition. These and other risks and uncertainties are discussed more fully in our filings with the Securities and Exchange Commission. Readers are encouraged to review the section titled "Risk Factors" in the Company's Annual Report on Form 10-K for the year ended December 31, 2023, as well as other disclosures contained in the Prospectus and subsequent filings made with the Securities and Exchange Commission. Forward-looking statements contained in this announcement are made as of this date and the Company undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.

Disclosure

The information stated above was prepared by Aclarion and reflects solely the opinion of Aclarion. Nothing in this statement shall be construed to imply any support or endorsement of Aclarion or any of its products by The London Clinic. Mr. Blease is a shareholder in Aclarion.

Investor Contacts:

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PCG Advisory, Inc.

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Media Contacts:

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SPRIG Consulting

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