UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13D


                    Under the Securities Exchange Act of 1934

                               (Amendment No. 1)


                               Pharmanetics, Inc.
                        --------------------------------
                                (Name of Issuer)

                                  Common Stock
                                  ------------
                         (Title of Class of Securities)

                                    71713J107
                                 (CUSIP Number)

                            Gregory Maloblocki, Esq.
                               Bayer Corporation
                                63 North Street
                                 Medfield, MA
                                  02052-1688

                                with a copy to:
                             Marilyn Mooney, Esq.
                           Fulbright & Jaworski L.L.P.
                           801 Pennsylvania Avenue, NW
                           Washington, D.C.  20004-2623
             ------------------------------------------------------
                  (Name, Address and Telephone Number of Person
               Authorized to Receive Notices and Communications)

                                 January 1, 2003
             -------------------------------------------------------
             (Date of Event which Requires Filing of this Statement)

If the filing person has previously  filed a statement on Schedule 13G to report
the  acquisition  that is the subject of this  Schedule  13D, and is filing this
schedule because of ss.ss. 240.13d-1(e),  240.13d-1(f),  or 240.13d-1(g),  check
the following box. [ ]

Note:  Schedules  filed in paper format shall include a signed original and five
copies of this  Schedule,  including all exhibits.  See Rule 240.13d-7 for other
parties to whom copies are to be sent.

*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for  any  subsequent   amendment   containing   information  which  would  alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).



CUSIP No.  71713J107                                        Page 2 of 9 Pages

1          NAME OF REPORTING PERSON
           I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
           Bayer Corporation

2          CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
           (a) | |
           (b) [ ]

3          SEC USE ONLY


4          SOURCE OF FUNDS


5          CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
           ITEMS 2(d) OR 2(e)
           [ ]

6          CITIZENSHIP OR PLACE OF ORGANIZATION
           Indiana

                            7        SOLE VOTING POWER
                                     0
        NUMBER OF
          SHARES            8        SHARED VOTING POWER
       BENEFICIALLY                  2,050,000
         OWNED BY
           EACH             9        SOLE DISPOSITIVE POWER
        REPORTING                    0
          PERSON
           WITH             10       SHARED DISPOSITIVE POWER
                                     2,050,000

11         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           2,050,000

12         CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES SHARES
           [ ]

13         PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
           20.9%

14         TYPE OF REPORTING PERSON
           CO



CUSIP No.  71713J107                                       Page 3 of 9 Pages

1          NAME OF REPORTING PERSON
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
           Bayer Aktiengesellshaft

2          CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
           (a) | |
           (b) [ ]

3          SEC USE ONLY


4          SOURCE OF FUNDS


5          CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
           ITEMS 2(d) OR 2(e)
           [ ]

6          CITIZENSHIP OR PLACE OF ORGANIZATION
           Federal Republic of Germany

                            7        SOLE VOTING POWER
                                     0
        NUMBER OF
          SHARES            8        SHARED VOTING POWER
       BENEFICIALLY                  2,050,000
         OWNED BY
           EACH             9        SOLE DISPOSITIVE POWER
        REPORTING                    0
          PERSON
           WITH             10       SHARED DISPOSITIVE POWER
                                     2,050,000

11         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
           2,050,000

12         CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES SHARES
           [ ]

13         PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
           20.9%

14         TYPE OF REPORTING PERSON
           CO


1          NAME OF REPORTING PERSON
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
           Bayer HealthCare LLC

2          CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
           (a) | |
           (b) [ ]

3          SEC USE ONLY


4          SOURCE OF FUNDS


5          CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
           ITEMS 2(d) OR 2(e)
           [ ]

6          CITIZENSHIP OR PLACE OF ORGANIZATION
           Delaware

                            7        SOLE VOTING POWER
                                     0
        NUMBER OF
          SHARES            8        SHARED VOTING POWER
       BENEFICIALLY                  2,050,000
         OWNED BY
           EACH             9        SOLE DISPOSITIVE POWER
        REPORTING                    0
          PERSON
           WITH             10       SHARED DISPOSITIVE POWER
                                     2,050,000

11         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           2,050,000

12         CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES SHARES
           [ ]

13         PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
           20.9%

14         TYPE OF REPORTING PERSON
           00





CUSIP No.  71713J107                                          Page 4 of 9 Pages

Item 2.  Identity and Background.

     This  Statement is also  being filed  by Bayer  HealthCare LLC  ("BHC"),  a
Delaware limited liability company with  its principal executive offices located
at 511 Benedict Avenue, Tarrytown, NY  10591.  BHC is  a wholly owned subsidiary
of the  Company.  The Company  made  a  capital  contribution  of its  Shares of
Common Stock to BHC  effective  as of January 1, 2003.  BHC plans to  submit the
share certificates to the Issuer for reissuance in its name as record holder.

    Information as to the executive officers and directors of the Company, Bayer
and BHC is set forth in Exhibits A, B and C hereto.

     During the past five  years,  neither  BHC nor, to the Company's knowledge,
any of the  persons  listed in Exhibit A nor,  to Bayer's  knowledge, any of the
persons listed in  Exhibit B, nor to BHC's knowledge, any of the persons  listed
in Exhibit  C  has been convicted  in a criminal  proceeding  (excluding traffic
violations and similar  misdemeanors).  During the past five years,  neither BHC
nor, to the  Company's knowledge, any of the persons listed in Exhibit A nor, to
Bayer's knowledge, any of the persons listed in Exhibit B, nor to BHC's
knowledge, any of the persons list in Exhibit C, has been a  party to a civil
proceeding of a judicial or administrative  body of competent jurisdiction and
as a result of such  proceeding  was  or  is  subject  to a  judgment, decree or
final  order enjoining future violations of, or  prohibiting or mandating
activities subject to, federal or  state securities  laws or finding any
violation  with respect to such laws.

Item 5.  Interest in Securities of the Issuer.

     (a) As  a  result  of  the  capital  contribution  from  the  Company,  BHC
beneficially  owns  the same  2,050,000  shares of  Common  Stock.  To the  best
knowledge of BHC, no director or executive officer thereof beneficially owns any
shares of Common Stock.

     (b) As the  Company and  BHC are  wholly owned  subsidiaries of  Bayer, the
Company, Bayer and BHC  share voting  and  investment  power over  the 2,050,000
shares.

     (c) The Company, Bayer and BHC have  not and, to the best  knowledge of the
Company, Bayer and BHC, no director or  executive officer of the  Company, Bayer
or BHC, has effected any transactions in the Common Stock during the past 60
days.


Item 6.  Contracts,  Arrangements,  Understandings or Relationships with Respect
to the Issuer.

    As previously reported in the Schedule 13D dated April 23, 2001, the Company
has  certain  preemptive  rights to  subscribe to  new securities  issued by the
Issuer on a  pro rata  basis.  The Company  waived  its  preemptive  rights with
respect to  the offering by  the  Issuer  of a  $9,580,000  private placement of
preferred stock  convertible into  common stock at $6.00 per  share and warrants
for  the purchase of  an additional  510,932 common  shares at  $7.12 per share.
In  connection  therewith, the  Issuer and  the  Company  entered  that certain
Amendment No. 1 to Common Stock Purchase  Agreement dated as of April 30, 2003.

     This  Amendment  modifies  and amends the  Company's  registration  rights,
preemptive  rights  and  transfer restrictions.  With  respect  to  registration
rights, the Amendment expands the number of demand registration rights available
to the Company as long as the Issuer  is  Form S-3  eligible,  provides  certain
piggyback registration  rights to  the Company, and addresses the allocation  of
registration rights as between the Company and holders of the Series B Preferred
Stock.

     In addition, the  Amendment  allows the  Company's registration  rights and
preemptive rights to be  transferred  along with  any  transfer  of  its shares.
Finally, the  Amendment alleviates  and clarifies certain  transfer restrictions
with respect to shares held by the Company.

     The  description of the Amendment is qualified in its entirety by reference
to such  amendment, a copy of which is  filed as an exhibit to this statement on
Schedule 13D.



CUSIP No.  71713J107                                      Page 5 of 9 Pages


Item 7.  Material to be Filed as Exhibits.


               Exhibit A    Information  concerning  the  Company's  executive
                            officers and directors.
               Exhibit B    Information  concerning Bayer's executive officers
                            and directors.
               Exhibit C    Information  concerning BHC's  executive  officers
                            and directors.
               Exhibit D    Amendment No. 1 to Common Stock Purchase Agreement
                            made as of April 30, 2003 between Pharmanetics, Inc.
                            and Bayer Corporation




CUSIP No.  71713J107                                     Page 6 of 9 Pages



                                    Signature

    After  reasonable  inquiry and to the best of my  knowledge  and  belief,  I
certify that the  information  set forth in this  amendment to this statement is
true and correct.

Date:  October 14, 2003              BAYER CORPORATION


                                By:  /s/ Joseph A. Akers
                                     -------------------------
                                     Joseph A. Akers
                                     Executive Vice President,
                                     Chief Administrative and Financial Officer

                                     BAYER HEALTHCARE LLC


                                By:  /s/ Frank Wenzel
                                     ------------------------
                                     Frank Wenzel
                                     Vice President, Biltroller
                                     and Chief Accounting Officer



                                     BAYER AKTIENGESELLSHAFT


                                By:  /s/ Klaus Kuehn
                                     ------------------------
                                     Klaus Kuehn
                                     Member, Board of Management




                                                                       Exhibit A


                DIRECTORS AND EXECUTIVE OFFICERS OF BAYER CORPORATION

     The name, business address,  and present principal occupation or employment
of each of the  directors and executive  officers of Bayer  Corporation  are set
forth below.  Unless  otherwise  indicated,  the  business  address of each such
director and executive officer is Bayer Corporation, 100 Bayer Road, Pittsburgh,
PA  15205-9741.  All the  directors  and  executive  officers  listed  below are
citizens of the United States,  except for  Dr. Attila  Molnar,  Dr. Franz-Josef
Berners  and  Dr. Richard  Pott, who  are  citizens of  the  Federal Republic of
Germany, Ian Paterson, who is  a citizen of the  United Kingdom, and Emil Lansu,
who is a citizen of The Netherlands.



NAME AND BUSINESS ADDRESS                   PRESENT PRINCIPAL OCCUPATION OR EMPLOYMENT
- -------------------------                   -------------------------------------------
                                        
Dr. Attila Molnar.........................  Director, President and Chief Executive Officer
Dr. Franz-Joseph Berners..................  Director
  Bayer AG
  Bayer-Werk
  51368 Leverkusen
  Leverkusen, Germany
Dr. Richard Pott..........................  Director
  Bayer AG
  Bayer-Werk
  51368 Leverkusen
  Leverkusen, Germany
Joseph A. Akers...........................  Executive Vice President, Chief
                                            Administrative and Financial Officer
Gary S. Balkema...........................  Executive Vice President, Healthcare
  Bayer HealthCare LLC
  511 Benedict Avenue
  Tarrytown, NY 10591
Emil Lansu................................  Executive Vice President, CropScience
  Bayer CropScience LP
  2 TW Alexander Drive
  Research Triangle Park, NC  27709
Randall S. Dearth.........................  Executive Vice President, Chemicals
Ian Paterson..............................  Executive Vice President, Polymers




                                      A-1


                                                                       Exhibit B

                      DIRECTORS AND EXECUTIVE OFFICERS OF
                                   BAYER AG


     The name, business address,  and present principal occupation or employment
of each of the directors and executive officers of Bayer AG are set forth below.
Unless  otherwise  indicated,  the  business  address of each such  director  or
executive  officer  is Bayer  Aktiengesellschaft,  D-51368  Leverkusen,  Federal
Republic of Germany.  All the directors and executive  officers listed below are
citizens of  the Federal  Republic of Germany, except for Mr. Kornblum, who is a
U.S. citizen, Mr. Achleitner, who is a citizen of Austria and Mr. Ackermann, who
is a citizen of Switzerland.


NAME AND BUSINESS ADDRESS                   PRESENT PRINCIPAL OCCUPATION OR EMPLOYMENT
- -------------------------                 -------------------------------------------
                                        
Werner Wenning............................  Chairman, Board of Management.
Klaus Kuehn...............................  Member, Board of Management.
Dr. Udo Oels..............................  Member, Board of Management.
Richard Pott..............................  Member, Board of Management.
Dr. Manfred Schneider.....................  Chairman, Supervisory Board.
Erhard Gipperich..........................  Vice Chairman, Supervisory Board;
                                            Chairman, Works Council.
Dr. Paul Achleitner.......................  Member, Supervisory Board;
  Allianz AG                                Member of Board of Management, Allianz AG.
  Koniginstr. 28
  80802 Munchen, Germany
Dr. Josef Ackermann........................ Member, Supervisory Board;
  Deutsche Bank AG                          Spokesman of the Board of Managing Directors
  Taunusanlage 12                           and Chairman of the Group Executive Committee
  60325 Frankfurt, Germany                  of Deutsche Bank AG.
Karl-Josef Ellrich........................  Member, Supervisory Board; Chairman, Works
  Bayer AG, Dormagen Plant                  Council, Dormagen plant, Bayer AG.
  41538 Dormagen, Germany
Thomas Hellmuth...........................  Member, Supervisory Board;
  Bayer CropScience AG                      Agricultural Engineer, Langenfeld, Bayer AG.
  Elisabeth-Selbert-Str. 4a
  40764 Langenfeld, Germany
Prof. Dr. Ing. e.h. Hans-Olaf Henkel......  Member, Supervisory Board;
  Gottfried Wilhelm Leibniz e.V.            President of Leibniz Association;
  Friedrichstr. 81                          Vice President of the Federation of German Industry.
  10117 Berlin, Germany
Dr. h.c. Martin Kohlhaussen...............  Member, Supervisory Board; Chairman of
  Commerzbank AG                            the Supervisory Board, Commerzbank AG.
  Kaiserplatz
  60261 Frankfurt am Main, Germany
John Christian Kornblum...................  Member, Supervisory Board;
  Lazard & Co. GmbH                         Chairman of Bankhaus Lazard.
  Pariser Platz 4a
  10117 Berlin, Germany
Petra Kronen..............................  Member, Supervisory Board;
  Bayer AG, Uerdingen Plant                 Chairman, Works Council, Uerdingen
  47812 Krefeld, Germany                    plant, Bayer AG.




                                      B-1




NAME AND BUSINESS ADDRESS                    PRESENT PRINCIPAL OCCUPATION OR EMPLOYMENT
- -------------------------                  -------------------------------------------
                                        

Dr. Heinrich von Pierer...................  Member, Supervisory Board;
  Siemens AG                                President and Chief Executive Officer,
  Wittelsbacherplatz 2                      Siemens AG.
  80333 Munchen, Germany
Wolfgang Schenk...........................  Member, Supervisory Board;
                                            Graduate Engineer, Bayer AG.
Hubertus Schmoldt.........................  Member, Supervisory Board;
  IG Bergbau, Chemie, Energie               Chairman, German Mine, Chemical and
  Konigsworther Platz 6                     Power Workers Union.
  30167 Hannover, Germany
Dieter Schulte............................  Member, Supervisory Board;
  German Trade Union Federation DGB         Former Chairman of the German Unions Federation.
  10178 Berlin, Germany
Dipl.-Ing. Dr. Ing E.h. Jurgen Weber......  Member, Supervisory Board; Chairman of
  Deutsche Lufthansa AG                     the Management Board, Deutsche Lufthansa AG.
  von Gablenz - Str. 2 - 6
  50679 Koln, Germany
Sigfried Wendlandt........................  Member, Supervisory Board; North Rhine
  IG Bergbau, Chemie, Energie               District Secretary of the German Mine,
  Hans-Bockler - Str. 39                    Chemical and Power Workers Union.
  40476 Dusseldorf, Germany
Reinhard Wendt............................  Member, Supervisory Board; Printer, Walsrode,
  Wolff Walsrode AG                         Bayer AG.
  29655 Walsrode, Germany
Thomas de Win.............................  Member, Supervisory Board; Commercial Clerk,
                                            Pulheim, Bayer AG.
Prof. Dr. Ernst-Ludwig Winnacker..........  Member, Supervisory Board; University Professor.
  Deutsche Forschungsgemeinschaft
  Kennedyallee 40
  53175 Bonn, Germany
Dr. Hermann Wunderlich....................  Member, Supervisory Board.
  Arndtstrasse 8
  51519 Odenthal, Germany





                                                                       Exhibit C


                DIRECTORS AND EXECUTIVE OFFICERS OF BAYER HEALTHCARE LLC

     The name, business address,  and present principal occupation or employment
of each of the directors and executive officers of Bayer HealthCare LLC  are set
forth below.  Unless  otherwise  indicated,  the  business  address of each such
director and  executive officer  is Bayer  HealthCare LLC, 511  Benedict Avenue,
Tarrytown, NY  10591.  All the  directors  and executive officers  listed  below
are citizens of the United States,  except for Dr. Attila Molnar, Markus Arnold,
Dr. Gunnar  Riemann, Wolfgang Hartwig, and Dr. Frank Wenzel who are  citizens of
the Federal Republic of Germany, and Rolf Classon, who is a citizen of Sweden.



NAME AND BUSINESS ADDRESS                   PRESENT PRINCIPAL OCCUPATION OR EMPLOYMENT
- -------------------------                   -------------------------------------------
                                        
Dr. Attila Molnar.........................  Director and Chairman
  Bayer Corporation
  100 Bayer Road
  Pittsburgh, PA  15205-9741
Rolf A. Classon...........................  Director and President and CEO
Joseph A. Akers...........................  Director
  Bayer Corporation
  100 Bayer Road
  Pittsburgh, PA  15205-9741
Markus Arnold.............................  Director Senior Vice President and
                                            Senior Administrative Officer
Dr. Gunnar Riemann........................  President, Biological Products Division
  Bayer HealthCare LLC                      and Executive Vice President
  79 TW Alexander Drive
  Research Triangle Park, NC  27709
Gary S. Balkema...........................  President, Consumer Care Division
  Bayer HealthCare LLC                      and Executive Vice President
  36 Columbia Road
  P.O. Box 1910
  Morristown, NJ 07962
Wolfgang Hartwig..........................  Director Director President, Diagnostics Division
                                            and Executive Vice President
John B. Payne.............................  President, Animal Health Division
  Bayer HealthCare LLC                      and Senior Vice President
  12707 Shawnee Mission Parkway
  Shawnee, KS  66216-1846
Dr. Frank Wenzel..........................  Vice President, Biltroller
  Bayer Corporation                         and Chief Accounting Officer
  100 Bayer Road
  Pittsburgh, PA  15205-9741






                                                                  Exhibit D


                                                               Execution Version
                               AMENDMENT NO. 1 TO
                         COMMON STOCK PURCHASE AGREEMENT
     This Amendment No. 1 to Common Stock Purchase Agreement (the "Amendment")
is made as of April 30, 2003, between PharmaNetics, Inc, a North Carolina
corporation (the "Company"), and Bayer Corporation, an Indiana corporation (the
"Purchaser").
                                    RECITALS
     WHEREAS, the Company and the Purchaser are parties to that certain Common
Stock Purchase Agreement dated as of April 23, 2001 (the "Common Stock Purchase
Agreement"); and
     WHEREAS, the Company and the Purchaser desire to amend the registration
rights and preemptive rights granted to the Purchaser pursuant to Sections 7.6
and 7.9, respectively, of the Common Stock Purchase Agreement and certain
restrictions on the transfer of Common Stock set forth in Section 8.6(b) of the
Common Stock Purchase Agreement.
     NOW, THEREFORE, in consideration of the premises and mutual covenants set
forth herein, and for other good and valuable consideration, the receipt and
sufficiency of which are hereby acknowledged, the parties hereto agree as
follows:
  Section 1. Amendments to the Common Stock Purchase Agreement.
     1.1 Section 7.6 of the Common Stock Purchase Agreement is hereby amended
and restated in its entirety to read as follows:
     7.6 Registration Rights.
         (a) Demand Registration.
             (i) At any time on or after the date hereof, the Covered Holders,
provided the registration rights hereunder have not lapsed as set forth in
Section 7.6(i) hereof, may demand in writing that the Company effect a
registration under the Securities Act of all or any portion of the Registrable
Securities then outstanding. Without limiting the foregoing, so long as the
Company is S-3 Eligible, then the Covered Holders shall also have the right, on
not more than one occasion every six months, to require the Company to register
for offer and sale pursuant to a Registration Statement on Form S-3 if so
requested by a majority of the Covered Holders (which majority shall be
calculated based on the number of Registrable Securities held by all Covered
Holders) all or a portion of the Registrable Securities then outstanding with an
expected aggregate offering price of at least $1,000,000; provided, however,
that the Covered Holders may request registration of any amount of Registrable
Securities where the request relates to all remaining Registrable Securities for
the purpose of sale in the manner specified in such demand. Such demand shall
also specify the number of Registrable Securities that the Covered Holders wish
to have so registered. Each registration of Registrable Securities made pursuant
to this Subsection (i) shall be a "Demand Registration." The Company shall
prepare and file a registration statement on any available form of registration
statement (the "Demand

Registration Statement"), for the public sale of the Registrable Securities as
soon as practicable; provided, however, that if the Company shall furnish to the
holders of Registrable Securities participating in a Demand Registration (the
"Participating Holders") a certificate signed by the Chairman or President of
the Company stating that in the good faith judgment of the Board of Directors of
the Company, that such Demand Registration would materially and adversely affect
any proposed or pending material acquisition, merger, business combination or
other material transaction involving the Company and that such disclosure is not
in the best interests of the Company and its shareholders, the Company shall
have the right (i) to postpone (or, if necessary or advisable, withdraw) the
filing, or delay the effectiveness, of a registration statement, (ii) to fail to
keep such registration statement Continuously Effective and (iii) not to amend
or supplement the registration statement or included prospectus after the
effectiveness of the registration statement; provided that no one such
postponement shall exceed 90 days in any six-month period and all such
postponements shall not exceed 120 days in the aggregate in any 12-month period.
The Company shall advise the Covered Holders of any such determination as
promptly as practicable. Upon written notice from the Company to the
Participating Holders delivered within 30 days of a demand to register
Registrable Securities under this Section 7.6(a), the Covered Holders' right to
demand registration pursuant to this Section 7.6(a) shall be suspended during
the period commencing 7 days prior to and ending 90 days following the effective
date of a registration statement for an underwritten public offering of the
Common Stock.
               (ii)  All Participating Holders proposing to distribute
securities through such registration shall enter into an underwriting agreement
with the managing or lead managing underwriter in the form customarily used by
such underwriter with such changes thereto as the parties thereto shall agree.
If any Participating Holder disapproves of the terms of any such underwriting,
it may elect to withdraw therefrom by written notice to the Company and the
managing or lead managing underwriter. Any Registrable Securities so withdrawn
from such underwriting shall be withdrawn from such registration.
               (iii) Whenever a registration is demanded pursuant to this
Section 7.6(a), unless a managing or lead managing underwriter objects thereto,
the Company may include in such registration securities for offering by the
Company and any other holder of securities, it being understood, however, that
the Company's and such other holder's right of inclusion in such registration
shall be subordinate to, and not pari passu with, the rights of the
Participating Holders.
               (iv)  If the managing underwriter thereof determines that the
total number of shares of Registrable Securities to be sold in such offering
shall be limited due to market conditions or otherwise, the reduction in the
total number of shares offered shall be made in accordance with Section
7.6(b)(ii).
               (v)   The Participating Holders shall have the right to select
the underwriter or underwriters and manager or managers to administer such
offering; provided, however, that each Person so selected shall be acceptable to
the Company in its reasonable judgment.
                                       2

               (vi)   The Company shall be obligated to effect not more than two
Demand Registrations; provided, however, that the Covered Holders may make
unlimited Demand Registration requests in accordance with Subsection (i) so long
as the Company is S-3 Eligible. For purposes of the preceding sentence, a Demand
Registration shall not be deemed to have been effected (i) unless a Demand
Registration Statement with respect thereto has become effective, (ii) if after
such Demand Registration Statement has become effective, such Demand
Registration Statement or the related offer, sale or distribution of Registrable
Securities thereunder is interfered with by any stop order, injunction or other
order or requirement of the SEC or other governmental agency or court for any
reason not attributable to the Participating Holders and such interference is
not thereafter eliminated, (iii) if the conditions to closing specified in the
underwriting agreement entered into in connection with such registration are not
satisfied or waived, other than by reason of a failure on the part of the
Participating Holders, (iv) upon the Company availing itself of Subsection (i)
above or (v) the number of shares of Registrable Securities to be sold by the
Covered Holders requesting a Demand Registration were reduced pursuant to
Subsection (iv) above. If the Company shall have complied with its obligations
under this Agreement, a right to demand a registration pursuant hereto shall be
deemed to have been satisfied upon the earlier of (x) the date as of which all
of the Registrable Securities included therein shall have been distributed
pursuant to the Demand Registration Statement, and (y) the date as of which such
Demand Registration shall have been Continuously Effective for a 90-day period
or other period specified herein (not to exceed 120 days) following the
effectiveness of such Demand Registration Statement, provided no stop order or
similar order, or proceedings for such an order, is thereafter entered or
initiated.
               (vii)  The Company shall use the Company's commercially
reasonable efforts to keep the relevant registration statement Continuously
Effective, if a Demand Registration Statement, for up to 90 days or until such
earlier date as of which all the Registrable Securities under the Demand
Registration Statement shall have been disposed of in the manner described in
the Registration Statement, or such longer period (but in no event longer than
120 days) as in the judgment of counsel for the underwriters a prospectus is
required by law to be delivered in connection with sales of Registrable
Securities by an underwriter or dealer in accordance with plan of distribution
included in such Demand Registration Statement. Notwithstanding the foregoing,
if for any reason the effectiveness of a Demand Registration Statement pursuant
to this Subsection is delayed or suspended or filing of the Demand Registration
Statement or seeking effectiveness thereof is postponed as permitted herein, the
commencement of the foregoing period shall be extended by the aggregate number
of days of such suspension or postponement.
               (viii) Except for registration statements on Forms S-4, S-8 or
any successor thereto, the Company will not file with the SEC any other
registration statement with respect to its capital stock, whether for its own
account or that of other stockholders, from the date of receipt of a notice from
requesting holders pursuant to this Section 7.6 until the completion of the
period of distribution of the registration contemplated thereby.
            (b) Piggy-back Registration.
               (i)    If at any time the Company intends to file on its behalf
or on behalf of any of its shareholders (including Covered Holders, with respect
to Registrable Securities, and
                                        3

eligible holders of Series B Registrable Securities) a registration statement in
connection with a public offering of any securities of the Company on a form and
in a manner that would permit the registration for offer and sale under the
Securities Act of Registrable Securities held by a Covered Holder, other than a
registration statement on Form S-8 or Form S-4 or any successor form or other
forms promulgated for similar purposes, then the Company shall give written
notice (an "Intended Offering Notice") of such intention to each Covered Holder
at least 30 business days prior to the anticipated filing date of such
registration statement. Such Intended Offering Notice shall offer to include in
such registration statement for offer to the public such number or amount of
Registrable Securities as each such Covered Holder may request, subject to the
conditions set forth herein, and shall specify, to the extent then known, the
number and class of securities proposed to be registered, the proposed date of
filing of such registration statement, any proposed means of distribution of
such securities, any proposed managing underwriter or underwriters of such
securities and (if available or as soon as available) a good faith estimate
(which may be a range) by the Company of the proposed maximum offering price of
such securities, as such price is proposed to appear on the facing page of such
registration statement. Any Covered Holder desiring to have Registrable
Securities included in such registration statement and offered to the public
shall so advise the Company in writing (the written notice of any such Covered
Holder being a "Piggy-back Notice") not later than 10 business days after the
Company's delivery to the Covered Holders of the Intended Offering Notice,
setting forth the number of Registrable Securities such Covered Holder desires
to have included in the registration statement and offered to the public. Upon
the request of the Company, such Covered Holders shall enter into such
underwriting, custody and other agreements as shall be customary in connection
with registered secondary offerings or necessary or appropriate in connection
with the offering.
               (ii) In connection with an underwritten offering, if the managing
underwriter or underwriters advise the Company in writing that in its or their
opinion the number of securities proposed to be registered exceeds the number
that can be sold in such offering, the Company shall include in such
registration the number of securities that, in the opinion of such managing
underwriter or underwriters, can be sold as follows: (i) first, the securities
that the Company proposes to sell on its behalf or, if the offering is a Demand
Registration the securities proposed to be sold, for the shareholder or
shareholders initiating such Demand Registration, as the case may be, (ii)
second, holders of Registrable Securities and holders of Series B Registrable
Securities, pro rata among such holders and (iii) third, other securities
requested to be included in such registration; provided, however, the Covered
Holders and the eligible holders of Series B Registrable Securities desiring to
have securities included in such an underwritten offering (other than in the
case of a Demand Registration) shall not be reduced to less than 20 percent of
the aggregate securities to be sold in such offering, split in equal one-half
parts (10 percent each) between the Covered Holders and the holders of the
Series B Registrable Securities. Notwithstanding the provisions of this
Subsection (ii), if the registration was initiated at the request of the holders
of Series B Registrable Securities pursuant to their demand rights as set forth
in the Series B Registration Rights Agreement, priority in underwriter cutbacks
with respect to such registration shall be governed by the provisions of the
Series B Registration Rights Agreement, provided that the Covered Holders that
have requested inclusion of their securities to be included therein shall have
priority over any persons, other than Covered Holders as defined in the Series B
Registration Rights Agreement, holding securities requested to be included in
such registration, and the twenty percent requirement set forth in the previous
                                       4

sentence shall not apply to any such registration initiated at the request of
holders of Series B Registrable Securities.
             (iii) The rights of the Covered Holders pursuant to Subsections (a)
and (b) hereof are cumulative, and the exercise of rights under one such
Subsection shall not exclude the subsequent exercise of rights under the other
such Subsection. Notwithstanding anything herein to the contrary, the Company
may abandon and/or withdraw any registration (other than pursuant to Subsection
(a) hereof) as to which any right under this Subsection (b) may exist at any
time and for any reason without liability hereunder. In such event, the Company
shall so notify each Covered Holder that has delivered a Piggy-back Notice to
participate therein.
             (iv)  Except for registration rights granted by the Company after
the date hereof which are subordinate to the rights of the Covered Holders
pursuant to Subsection (a) hereof and this Subsection (b), prior to the
termination of this Agreement, the Company shall not grant any registration
rights to any other Person without the consent of holders of a majority of the
Registrable Securities then outstanding.
         (c) Registration Statement Information Relating to the Covered Holders.
Each Covered Holder shall promptly upon receipt of written request provide the
Company or any underwriter or counsel participating or otherwise involved in any
such registration with any information relating to the Covered Holder or the
Registrable Securities that is reasonably required to be included in the
registration statement or the prospectus, or any amendment thereof, relating to
such offering or required to cause the registration to be declared and remain
effective. Such information shall be submitted in writing, signed by the Covered
Holder, or a duly authorized representative or agent thereof, and shall state
that the information is submitted specifically for the purpose of inclusion in
the registration statement, prospectus, offering circular or other document
related to the registration or qualification of the Registrable Securities
pursuant hereto. If the Covered Holder fails within a reasonable time to provide
such information, the Company may exclude from such registration the Registrable
Securities requested by the Covered Holder to be included therein.
         (d) Registration Procedures. If and whenever the Company is required to
effect the registration of any Registrable Securities of a Covered Holder
pursuant hereto, the Company will:
             (i)   prepare and file with the SEC a registration statement with
respect to such Registrable Securities and use reasonable efforts to cause such
registration statement to become and remain effective as provided herein;
provided, however, that before filing a registration statement or prospectus or
any amendments or supplements thereto, including documents incorporated by
reference after the initial filing of the registration statement and prior to
effectiveness thereof, the Company shall furnish to counsel for each Covered
Holder participating in the registration and underwriters, copies of all such
documents in the form substantially as proposed to be filed with the SEC at a
reasonable time prior to filing for review and comment by such counsel;
             (ii)  prepare and file with the SEC such amendments and supplements
to such registration statement and the prospectus used in connection with such
registration
                                        5

statement as may be necessary to comply with the provisions of the Securities
Act and rules thereunder with respect to the distribution of all securities
covered by such registration statement and as may be reasonably requested by a
Covered Holder participating in the registration or necessary to keep such
registration statement effective. If the registration is for an underwritten
offering, the Company shall amend the registration statement or supplement the
prospectus whenever required by the terms of the underwriting agreement. Pending
such amendment or supplement each Covered Holder participating in the
registration, upon written notice by the Company, shall cease making offers or
Transfers of Registrable Securities pursuant to the prior prospectus. In the
event that any Registrable Securities included in a registration statement
subject to, or required by, this Agreement remain unsold at the end of the
period during which the Company is obligated to use its commercially reasonable
efforts to maintain the effectiveness of such registration statement, the
Company may file a post-effective amendment to the registration statement for
the purpose of removing such securities from registered status;
             (iii) notify each Covered Holder participating in the registration
and the Underwriters' Representative and (if requested) confirm such advise in
writing, as soon as practicable after notice thereof is received by the Company
(i) when a registration statement or any amendment thereto has been filed or
becomes effective, the prospectus or any amendment or supplement to the
prospectus included therein has been filed, and, to furnish each Covered Holder
participating in the registration and the underwriters with copies thereof, (ii)
of any request by the SEC for amendments or supplements to the registration
statement or the prospectus included therein or for additional information,
(iii) if at any time the representations and warranties of the Company cease to
be true and correct, and (iv) of the receipt by the Company of any notification
with respect to the suspension or qualification of the Registrable Securities
for offering or sale in any jurisdiction or the initiation or threatening of any
proceeding for such purpose;
             (iv)  immediately notify each Covered Holder participating in the
registration, at any time when a prospectus relating thereto is required to be
delivered under the Securities Act, of the happening of any event as a result of
which the prospectus included in the registration statement, as then in effect,
includes an untrue statement of a material fact or omits to state any material
fact required to be stated therein or necessary to make the statements therein
not misleading in the light of the circumstances then existing, and if it is
necessary, in the opinion of counsel to the Company, to prepare and file with
the SEC such amendments and supplements to such registration statement and the
prospectus used in connection therewith as may be necessary to keep such
registration statement effective and current and to comply with the provisions
of the Securities Act with respect to the sale or other disposition of all
shares covered by such registration statement, including such amendments and
supplements as may be necessary to reflect the intended method of disposition
from time to time of each Covered Holder participating in the registration if
the registration is effected in connection with an offering which is not
underwritten;
             (v)   cooperate with each Covered Holder participating in the
registration and the Underwriters' Representatives to facilitate the timely
preparation and delivery of certificates representing Registrable Securities to
be sold and not bearing any restrictive legends; and enable such Registrable
Securities to be in such denomination and
                                       6

registered in such names as the Underwriters' Representative may request at
least two business days prior to the sale of Registrable Securities to the
underwriters;
             (vi)   cooperate with each Covered Holder participating in the
registration in connection with any filings required to be made with the NASD,
and otherwise use its best efforts to comply with the rules, by-laws and
regulations of the NASD as they apply to the registration;
             (vii)  furnish to each Covered Holder participating in the
registration such number of copies of a prospectus, including a preliminary
prospectus and any amendments and any supplements thereto, in conformity with
the requirements of the Securities Act, as each Covered Holder participating in
the registration may reasonably request in order to facilitate the public sale
or other disposition of the Registrable Securities owned by such Covered Holder;
             (viii) use reasonable efforts to register or qualify the
Registrable Securities covered by such registration statement under such other
securities or blue sky or other applicable laws of such jurisdictions within the
United States as each Covered Holder participating in the registration shall
reasonably request to enable such Covered Holder to consummate the public sale
or other disposition of the Registrable Securities owned by the Covered Holder,
and to obtain the withdrawal of any order suspending the effectiveness of a
registration statement, or the lifting of any suspension of the qualification
(or exemption from qualification) of the offer and Transfer of any of the
Registrable Securities in any jurisdiction, at the earliest possible moment;
except that the Company shall not for any such purpose be required (i) to
qualify generally to do business as a foreign corporation in any jurisdiction in
which it would not be required to so qualify but for such registration or
qualification, (ii) to subject itself to taxation in any such jurisdiction, or
(iii) to consent to general service of process in any such jurisdiction;
             (ix)   use its best efforts to furnish to each Covered Holder who
has included Registrable Securities in the registration statement a signed
counterpart, addressed to the Covered Holder, of (A) an opinion of counsel for
the Company, dated the date of the closing under the underwriting agreement, and
(B) a "cold comfort" letter signed by the independent public accountants who
have issued a report on the Company's financial statements included in such
registration statement dated the date of effectiveness of the registration
statement and the date of the closing under the underwriting agreement, covering
substantially the same matters with respect to such registration statement (and
the prospectus included therein) and, in the case of such accountants' letters,
with respect to events subsequent to the date of such financial statements, as
are customarily covered in opinions of issuer's counsel and in accountants'
letters delivered to underwriters in underwritten public offerings of securities
and, in the case of the accountants' letters, such other financial matters as
such Covered Holder may reasonably request;
             (x)    otherwise use its best efforts to comply with all applicable
rules and regulations of the SEC, and make available to its security holders, as
soon as reasonably practicable, an earnings statement covering the period of at
least 12 months, beginning with the first month of the first fiscal quarter
after the effective date of such registration statement, which earnings
statement shall satisfy the provisions of Section 11(a) of the Securities Act;
                                        7

             (xi)   use its best efforts to list such Registrable Securities on
each securities exchange or over-the-counter market on which shares of Common
Stock are then listed, if such Registrable Securities are not already so listed
and if such listing is then permitted under the rules of such exchange and, if
shares of Common Stock are not then listed on a securities exchange or
over-the-counter market, to use its best efforts to cause such Registrable
Securities to be listed on such securities exchange or over-the-counter market
as the managing or lead managing underwriter shall reasonably request;
             (xii)  use its best efforts to provide a transfer agent and
registrar for such Registrable Securities not later than the effective date of
such registration statement;
             (xiii) if requested by the managing or lead managing underwriter
for any underwritten offering that includes any Registrable Securities, enter
into an underwriting agreement with the underwriters of such offering, such
agreement to contain such representations and warranties by the Company and such
other terms and conditions as are contained in underwriting agreements
customarily used by such managing or lead managing underwriter with such changes
as the parties thereto shall agree, including, without limitation, provisions
relating to indemnification and contribution in lieu thereof;
             (xiv)  cooperate with each Covered Holder participating in the
registration, and the Underwriters' Representative for such offering in the
marketing, and customary selling efforts relating to the Registrable Securities,
including participating for a period not in excess of five (5) business days per
Demand Registration in customary "road show" presentations as may be reasonably
requested by the Underwriters' Representative;
             (xv)   promptly notify each Covered Holder participating in the
registration of any stop order issued or threatened to be issued by the SEC in
connection therewith and take all reasonable actions required to prevent the
entry of such stop order or to remove it if entered; and
             (xvi)  make available for inspection by each Covered Holder
participating in the registration, any underwriter participating in such
offering and the representatives of such Covered Holder and such underwriter all
financial and other information as shall be reasonably requested by them, and
provide the Covered Holder, any underwriter participating in such offering and
the representatives of the Covered Holder and such underwriter the reasonable
opportunity to discuss the business affairs of the Company with its principal
executives and independent public accountants who have certified the audited
financial statements included in such registration statement, in each case all
as necessary to enable them to exercise their due diligence responsibilities
under the Securities Act; provided, however, that information that the Company
determines, in its reasonable and good faith judgment, to be confidential and
which the Company advises such Person in writing, is confidential shall not be
disclosed unless such Person signs a confidentiality agreement reasonably
satisfactory to the Company.
         (e) Termination of Sales. During the effective period of any
registration statement covering Registrable Securities, each Covered Holder will
not effect sales thereof after receipt of telegraphic or written notice from the
Company to suspend sales to permit the
                                       8

Company to correct or update a registration statement or prospectus until such
Covered Holder receives written notice from the Company that the registration
statement or prospectus has been corrected or updated. At the end of the
effective period of any registration statement covering any Registrable
Securities, each Covered Holder participating in the registration shall
discontinue sales of shares pursuant to such registration statement upon receipt
of notice from the Company of its intention to remove from registration the
shares covered by such registration statement which remain unsold, and such
Covered Holder shall notify the Company of the number of shares registered which
remain unsold immediately upon receipt of such notice from the Company.
          (f) Expenses of Registration. With respect to the registrations
effected pursuant to Subsections (a) and (b) hereof, the Company shall bear and
pay all expenses incurred in connection with any registration, filing, or
qualification of Registrable Securities with respect to such registrations,
including all registration, filing and NASD fees, all fees and expenses of
complying with securities or blue sky laws, all word processing, duplicating and
printing expenses, messenger and delivery expenses, the reasonable fees and
disbursements of counsel for the Company, and of the Company's independent
public accountants, including the expenses of any special audits or "cold
comfort" letters required by or incident to such performance and compliance,
premiums and other costs of policies of insurance obtained by the Company
against liabilities arising out of the public offering of Registrable Securities
being registered and the reasonable fees and disbursements of one counsel
designated by the majority of Covered Holders participating in the registration
(the "Registration Expenses"), but in no event shall the Company bear
underwriting discounts and commissions and transfer taxes relating to
Registrable Securities or fees and expenses of more than one counsel to the
Covered Holders participating in the registration and provided that the Company
shall not be required to pay for any expenses of any registration begun pursuant
to Subsection (a) if the registration is subsequently withdrawn at the request
of the Covered Holders making the demand (in which case the Covered Holders
shall bear such expense), other than by reason of failure of the Company to
comply with its covenants contained herein unless the Covered Holders making the
demand agrees that such withdrawn registration shall constitute one of the
Demand Registrations under Subsection (a) hereof.
          (g) Indemnification.
              (i)   In any registration in which a Covered Holder participates,
the Company will indemnify such Covered Holder and each underwriter and selling
broker for each Covered Holder and each officer and director of each Covered
Holder and each person, if any, who controls such Covered Holder or any such
underwriter or broker within the meaning of Section 15 of the Securities Act,
against all claims, losses, damages, expenses and liabilities (or actions in
respect thereof), including any of the foregoing incurred in settlement of any
litigation, commenced or threatened, arising out of or based on any untrue
statement (or alleged untrue statement) of a material fact contained in any
preliminary prospectus or amended preliminary prospectus or in the prospectus,
offering circular or other document incident to any registration, qualification
or compliance (or in any related registration statement, notification or the
like) as such may be amended or supplemented from time to time or any omission
(or alleged omission) to state therein a material fact required to be stated
therein or necessary to make the statements therein, in light of the
circumstances under which they were made, not misleading, or any violation by
the Company of the Securities Act or any rule or regulation promulgated
thereunder
                                        9

or any state securities laws or regulations applicable to the Company in
connection with any such registration, qualification or compliance, and will
reimburse each Covered Holder and each such underwriter, broker and controlling
person for any legal and any other expenses reasonably incurred, as such
expenses are incurred, in connection with investigating or defending any such
claim, loss, damage, liability or action; provided, however, that the Company
will not be liable in any such case to the extent that any such claim, loss,
damage or liability arises out of or is based on any untrue statement or
omission made in reliance upon and in conformity with written information
furnished to the Company in an instrument executed by a Covered Holder or the
underwriter for a Covered Holder or any representative of a Covered Holder or
the underwriter for a Covered Holder and stated to be specifically for use
therein.
              (ii)  In any registration in which a Covered Holder participates,
such Covered Holder will indemnify the Company and its officers and directors,
each person, if any, who controls any thereof within the meaning of Section 15
of the Securities Act and their respective successors and any underwriter for
the Company for such registration and each other security holder participating
in the registration against all claims, losses, damages, expenses and
liabilities (or actions in respect thereof) arising out of or based on any
untrue statement (or alleged untrue statement) of a material fact contained in
any preliminary prospectus or amended prospectus or in the prospectus, offering
circular or other document incident to any registration statement, qualification
or compliance (or in any related registration statement, notification or the
like) as such may be amended or supplemented from time to time or any omission
(or alleged omission) to state therein a material fact required to be stated
therein or necessary to make the statements therein, in light of the
circumstances under which they were made, not misleading, and will reimburse the
Company and each other person indemnified pursuant to this paragraph (ii) for
any legal and any other expenses reasonably incurred, as such expenses are
incurred, in connection with investigating or defending any such claim, loss,
damage, liability or action; provided, however, that this paragraph (ii) shall
apply only if (and only to the extent that) such statement or omission was made
in reliance upon and in conformity with written information (including, without
limitation, written negative responses to inquiries) furnished to the Company
specifically for inclusion in the prospectus, offering circular, or other
document incident to the registration statement by an instrument duly executed
by the Covered Holder or its representatives, and as to which the Company had no
actual knowledge. Notwithstanding the foregoing, the liability of a Covered
Holder under this Subsection (ii) shall be limited to an amount equal to the
aggregate proceeds received by the Covered Holder from the sale of its shares in
such registration, unless such liability arises out of or is based on willful
misconduct by the Covered Holder.
              (iii) Each party entitled to indemnification hereunder (the
"Indemnified Party") shall give notice to the party required to provide
indemnification (the "Indemnifying Party") promptly after such Indemnified Party
has actual knowledge of any claim as to which indemnity may be sought, and shall
permit the Indemnifying Party (at its expense) to assume the defense of any
claim or any litigation resulting therefrom, provided that counsel for the
Indemnifying Party, who shall conduct the defense of such claim or litigation,
shall be satisfactory to the Indemnified Party, and the Indemnified Party may
participate in such defense at such party's expense, and provided, further, that
the omission by any Indemnified Party to give notice as provided herein shall
not relieve the Indemnifying Party of its obligations under this Section 7.6(g)
except to the extent that the omission results from a failure of actual notice
to the
                                       10

Indemnifying Party by the Indemnified Party and such Indemnifying Party is
damaged solely as a result of the failure to give notice; and provided further,
however, that the Indemnifying Party shall not be entitled to assume the defense
for matters as to which there is, in the opinion of counsel to the Indemnified
Party, a conflict of interest or separate and different defenses. No
Indemnifying Party, in the defense of any such claim or litigation, shall,
except with the consent of each Indemnified Party, consent to entry of any
judgment or enter into any settlement which does not include as an unconditional
term thereof the giving by the claimant or plaintiff to such Indemnified Party
of a release from all liability in respect of such claim or litigation.
              (iv)  The payments with respect to any indemnity required by this
Section 7.6(g) shall be made by periodic payments during the course of the
investigation or defense, as and when bills are received or expenses incurred,
upon submission of supporting invoices or other claims for payment, including
any calculations necessary to pro-rate any amounts payable pursuant to the
indemnity.
          (h) Contribution.
              (i)   If the indemnification provided for in Section 7.6(g) hereof
is unavailable to the Indemnified Parties in respect of any losses, claims,
damages, liabilities or expenses (or actions in respect thereof) referred to
therein, then each such Indemnifying Party, in lieu of indemnifying such
Indemnified Party, shall contribute to the amount paid or payable by such
Indemnified Party as a result of such losses, claims, damages, liabilities or
expenses (or actions in respect thereof) in such proportion as is appropriate to
reflect the relative fault of the Indemnifying Party on the one hand and the
Indemnified Party on the other in connection with the statement or omission
which resulted in such losses, claims, damages, liabilities or expenses (or
actions in respect thereof), as well as any other relevant equitable
considerations. The relative fault shall be determined by reference to, among
other things, whether the untrue statement (or alleged untrue statement) of a
material fact or the omission (or alleged omission) to state a material fact
relates to information supplied by the Indemnifying Party or the Indemnified
Party and the parties' relative intent, knowledge, access to information and
opportunity to correct or prevent such statement or omission. The Company and
each Covered Holder agree that it would not be just and equitable if
contribution pursuant to this Section 7.6(h) were determined by pro rata
allocation or by any other method of allocation which does not take account of
the equitable considerations referred to above. The amount paid or payable by an
Indemnified Party as a result of the losses, claims, damages, liabilities or
expenses (or actions in respect thereof) referred to above in this Section
7.6(h) or in Section 7.6(g) shall be deemed to include any legal or other
expenses reasonably incurred by such Indemnified Party in connection with
investigating or defending any such action or claim.
              (ii)  Notwithstanding anything to the contrary contained herein,
the obligation of a Covered Holder to contribute pursuant to this Section 7.6(h)
is several and not joint and a Covered Holder shall not be required to
contribute any amount in excess of the amount by which the total price at which
the shares of the Covered Holder were offered to the public exceeds the amount
of any damages which the Covered Holder has otherwise been required to pay by
reason of such untrue statement (or alleged untrue statement) or omission (or
alleged omission).
                                       11

              (iii) No person guilty of fraudulent misrepresentation (within the
meaning of Section 11 (f) of the Securities Act) shall be entitled to
contribution from any person who was not guilty of such fraudulent
misrepresentation.
          (i) Rule 144 Requirements. The Company shall make whatever filings
with the SEC or otherwise and undertake to make publicly available and available
to each Covered Holder, pursuant to Rule 144 of the SEC under the Securities Act
(or any successor rule or regulation), such information as is necessary to
enable a Covered Holder to make sales of Registrable Securities pursuant to that
Rule. The Company shall furnish to a Covered Holder, upon request, a written
statement executed by the Company as to the steps it has taken to comply with
the current public information requirements of Rule 144.
          (j) Survival and Termination of Rights. The agreements and covenants
contained in this Section 7.6 shall be continuing and shall survive any Transfer
of the Shares to any Person who is a Covered Holder. However, the rights of
Covered Holders to cause the Company to register their Registrable Securities
hereunder shall terminate with respect to such securities and such securities
shall no longer be deemed to be Registrable Securities following a bona fide,
firmly underwritten public offering of such Registrable Securities under the
Securities Act resulting in less than 20% of the Registrable Securities
remaining outstanding or at such time as the Covered Holders are able to dispose
of all of their Registrable Securities in one three-month period pursuant to the
provisions of Rule 144.
          (k) Sales During Registration. If so requested by the Underwriters'
Representative in connection with an offering of any Registrable Securities, the
Company shall agree not to effect any sale or distribution of shares of Common
Stock during the 7-day period prior to, and during the 90-day period beginning
on, the date a registration statement is declared effective under the Securities
Act by the SEC. The Company agrees to use its commercially reasonable efforts to
obtain from each holder of restricted securities of the Company the same as or
similar to those being registered by the Company on behalf of each Covered
Holder, or any restricted securities convertible into or exchangeable or
exercisable for any of its securities, an agreement not to effect any sale or
distribution of such securities (other than securities purchased in a public
offering) during any period referred to in this paragraph, except as part of any
such registration statement if permitted. Without limiting the foregoing, if the
Company grants any Person (other than a holder of Registrable Securities) any
rights to demand or participate in a registration, the Company agrees that the
agreement with respect thereto shall include such Person's agreement as
contemplated by the previous sentence.
     1.2  Section 7.9 of the Common Stock Purchase Agreement is hereby amended
and restated in its entirety to read as follows:
          7.9 Preemptive Rights. The Company shall, prior to any issuance by the
     Company of any of its securities (other than debt securities with no equity
     feature), offer to each Covered Holder by written notice the right, for a
     period of thirty (30) days, to purchase the Covered Holder's Pro Rata Share
     (as such term is defined below) of such securities for cash at a price
     equal to the price or other consideration for which such securities are to
     be issued; provided, however, that the preemptive rights of each Covered
     Holder pursuant to this Section 7.9 shall not apply to securities issued
     (A) upon
                                       12

     conversion of any shares of the Preferred Stock outstanding on the Closing
     Date (B) as a stock dividend or upon any subdivision of shares of Common
     Stock, provided that the securities issued pursuant to such stock dividend
     or subdivision are limited to additional shares of Common Stock, (C)
     pursuant to options or other rights which are issued pursuant to the 1994
     or 1995 Stock Option Plans or any similar plan approved by the Board of
     Directors of the Company and the holders of Voting Securities within one
     year of such Board approval or (D) in payment of dividend obligations on
     the Preferred Stock. The Company's written notice to each Covered Holder
     shall describe the securities proposed to be issued by the Company and
     specify the number, price and payment terms. A Covered Holder may accept
     the Company's offer as to the full number of securities offered to it or
     any lesser number by written notice thereof given by it to the Company
     prior to the expiration of the aforesaid thirty (30) day period, in which
     event the Company shall promptly sell and such Covered Holder shall buy,
     upon the terms specified, the number of securities agreed to be purchased
     by the Covered Holder. For purposes of this Section 7.9, a Covered Holder's
     "Pro Rata Share" of offered securities shall be determined by multiplying
     the full number of securities offered by the Company by a fraction, the
     numerator of which shall be the number of shares of Common Stock held by
     the Covered Holder as of the date of the Company's notice of offer and the
     denominator of which shall be the aggregate number of shares of Common
     Stock (calculated as aforesaid) held on such date by all holders of capital
     stock of the Company. The Company shall be free at any time following
     expiration of the thirty-day offer period and prior to ninety (90) days
     after the expiration of the thirty day offer period, to offer and sell to
     any third party or parties the number of the securities not agreed by the
     Covered Holders to be purchased by them, all at a price and on payment
     terms no less favorable to the Company than those specified in such notice
     of offer to the Covered Holders. However, if such third party sale or sales
     are not consummated within such ninety (90) day period, the Company shall
     not sell such securities as shall not have been purchased within such
     period without again complying with this Section 7.9.
     1.3  Section 8.6(b) of the Common Stock Purchase Agreement is hereby
amended and restated in its entirety to read as follows:
     8.6  Restrictions on Transfer of Voting Securities.
          (a) The Purchaser shall not, directly or indirectly, sell or Transfer
any Voting Securities for a period of one year commencing with the Closing Date.
          (b) Subject to Section 8.6(a), the Purchaser shall not, directly or
indirectly, sell or Transfer any Voting Securities, except
              (i)   to the Company or any person or group approved by the
Company;
              (ii)  to an Affiliate of the Purchaser, as long as such Affiliate
agrees to hold such Voting Securities subject to all the provisions of this
Agreement, including this Section 8.6;
              (iii) pursuant to Rule 144 under the Securities Act;
                                       13

              (iv)  pursuant to an effective registration statement under the
Securities Act;
              (v)   subject to the Company's right of first refusal as set forth
in Section 9.1 hereof, in transactions not otherwise described in this Section
8.6(b);
              (vi)  pursuant to a bona fide pledge of such Voting Securities to
an institutional lender to secure a loan, guarantee or other financial support,
provided that such lender agrees to hold such Voting Securities subject to all
provisions of this Agreement and any sale or disposition by such lender of such
pledged Voting Securities shall be subject to the limitations of this Section
8.6; or
              (vii) pursuant to a pro rata dividend to the stockholders of the
Purchaser.
     1.4  Section 10 of the Common Stock Purchase Agreement is hereby amended to
delete the defined term "Inclusion Notice" therefrom and to add thereto in the
appropriate alphabetical position the following new definitions:
     "Covered Holder" means (i) any member of the Purchaser Group and (ii) any
     other Person that holds a minimum of 20 percent of the Registrable
     Securities.
     "Demand Registration Statement" shall have the meaning set forth in Section
     7.6(a).
     "Intended Offering Notice" shall have the meaning set forth in Section
     7.6(b).
     "Piggy-back Notice" shall have the meaning set forth in Section 7.6(b).
     "S-3 Eligible" means that the Company meets the registrant requirements and
     transaction requirements for the use of Form S-3 (or any successor form
     thereto) of the SEC, as set forth in the General Instructions to such Form
     (or any successor form thereto).
     "Series B Registrable Securities" means any securities of the Company that
     may be "Registrable Securities" under the Series B Registration Rights
     Agreement.
     "Series B Registration Rights Agreement" means that certain Registration
     Rights Agreement dated as of April 30, 2003 by and among the Company and
     the shareholders listed on Exhibit A thereto.
     1.5  The second sentence of Section 11.5 of the Common Stock Purchase
Agreement is hereby amended in its entirety to read as follows:
     Except as otherwise provided in this Agreement, this Agreement may not be
     assigned by a party without the prior written consent of the other party
     except by operation of law and except, in the case of the Purchaser, to an
     Affiliate of the Purchaser or as otherwise provided in Section 8.6(b), in
     which case the assignee shall be subject to all of the provisions of this
     Agreement except as otherwise provided herein.
                                       14

   Section 2.  Definitions. All capitalized terms used herein and not otherwise
defined herein shall have the meanings ascribed thereto in the Common Stock
Purchase Agreement.
   Section 3.  Governing Law. This Amendment shall be governed in all respects
by the laws of the State of North Carolina as applied to contracts entered into
solely between residents of, and to be performed entirely within, such state.
   Section 4.  Entire Agreement. This Amendment, the Common Stock Purchase
Agreement, that certain letter agreement between the Company and the Purchaser
dated January 15, 2003 (the "Letter Agreement") and the other documents
delivered pursuant hereto constitute the full and entire understanding and
agreement between the parties with regard to the subject matter hereof and
thereof and supersede all prior agreements and understandings among the parties
relating to the subject matter hereof and in the Common Stock Purchase Agreement
and the Letter Agreement. No party shall be liable or bound to any other party
in any manner by any warranties, representations or covenants except as
specifically set forth herein or in the Common Stock Purchase Agreement or
Letter Agreement. This Amendment, the Common Stock Purchase Agreement, the
Letter Agreement or any term hereof or thereof may be amended, waived,
discharged or terminated other than by a written instrument signed by the party
against whom enforcement of any such amendment, waiver, discharge or termination
is sought.
   Section 5.  Counterparts. This Amendment may be executed in any number of
counterparts, each of which may be executed by fewer than all of the parties,
each of which shall be enforceable against the parties actually executing such
counterparts, and all of which together shall constitute one instrument.
   Section 6.  Severability. In the event that any provision of this Amendment
becomes or is declared by a court of competent jurisdiction to be illegal,
unenforceable or void, this Amendment shall continue in full force and effect
without said provision; provided, that no such severability shall be effective
if it materially changes the economic impact of this Amendment on any party.
   Section 7.  Headings. Headings of the various sections of this Amendment have
been inserted for convenience of reference only and shall not be relied upon in
construing this Amendment. Use of any gender herein to refer to any person shall
be deemed to comprehend masculine, feminine and neuter unless the context
clearly requires otherwise.
   Section 8.  Expenses. Each party hereto shall pay its own costs and expenses
incurred in connection herewith, including the fees of its counsel, auditors and
other representatives, whether or not the transactions contemplated herein are
consummated.
   Section 9.  Third Party Beneficiaries. Nothing in this Amendment shall create
or be deemed to create any rights in any person or entity not a party to this
Amendment except for such rights as may exist by virtue of any contract or other
agreement existing on the date hereof.
   Section 10. Attorneys' Fees. The prevailing party in any litigation between
any Covered Holder and the Company involving this Amendment shall be entitled to
recover from the other party its reasonable attorneys' fees and costs.
                                       15

   Section 11. Conflicts. To the extent any provision of this Amendment
conflicts with any provision of the Series B Registration Rights Agreement, the
provision contained in this Amendment shall govern.
   Section 12. Amendment. Sections 7.6, 7.9 and 8.6(b) of that certain Stock
Purchase Agreement dated August 28, 1998 (the "1998 Purchase Agreement") between
Cardiovascular Diagnostics, Inc. (predecessor to the Company) and Chiron
Diagnostics Corporation (predecessor to the Purchaser), as amended by Section
11.18 of the Common Stock Purchase Agreement, are hereby amended and restated in
their entirety in Sections 7.6, 7.9 and 8.6(b), respectively, of the Common
Stock Purchase Agreement as amended and restated in this Amendment. Sections 10
and 11.5 of the 1998 Purchase Agreement are hereby amended in Sections 10 and
11.5, respectively, of the Common Stock Purchase Agreement as amended by this
Amendment.
                     [The next page is the signature page.]
                                       16

IN WITNESS WHEREOF, the parties hereto have caused this Amendment to be executed
by their respective authorized officers as of the date first above written.
                                        PHARMANETICS, INC.
                                        By:  /s/ John Funkhouser
                                             --------------------------
                                             Name:  John Funkhouser
                                             Title: President
                                        BAYER CORPORATION
                                        By:  /s/ George J. Lykos
                                             --------------------------
                                             Name:  George J. Lykos
                                             Title: SVP, CLO and Secretary




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