MUS -- Converted by SEC Publisher, created by BCL Technologies Inc., for SEC Filing

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM N-Q

QUARTERLY SCHEDULE OF PORTFOLIO HOLDINGS OF REGISTERED
MANAGEMENT INVESTMENT COMPANY

Investment Company Act file number 811-08707

Name of Fund: BlackRock MuniHoldings Insured Fund, Inc. (MUS)

Fund Address: 100 Bellevue Parkway, Wilmington, DE 19809

Name and address of agent for service: Donald C. Burke, Chief Executive Officer, BlackRock
MuniHoldings Insured Fund, Inc., 800 Scudders Mill Road, Plainsboro, NJ, 08536. Mailing
address: P.O. Box 9011, Princeton, NJ, 08543-9011

Registrant’s telephone number, including area code: (800) 882-0052, Option 4

Date of fiscal year end: 04/30/2009

Date of reporting period: 05/01/2008 – 07/31/2008

Item 1 – Schedule of Investments

BlackRock MuniHoldings Insured Fund, Inc.             
Schedule of Investments July 31, 2008 (Unaudited)    (Percentages shown are based on Net Assets) 
 
            Par     
State    Municipal Bonds        (000)         Value 
 
 
 
 
Alabama - 1.2%    Jefferson County, Alabama, Limited Obligation School Warrants,         
    Series A, 5.50%, 1/01/22        $ 2,170    $ 2,056,509 
 
 
 
 
Arkansas - 4.5%    Arkansas State Development Finance Authority, M/F Mortgage Revenue         
    Refunding Bonds, Series C, 5.35%, 12/01/35 (a)(b)        7,420    7,436,473 
 
 
 
 
California - 17.7%    California State Public Works Board, Lease Revenue Bonds (Department         
    of General Services - Capitol East End Complex),             
    Series A, 5%, 12/01/27 (c)        2,000    1,975,460 
    California State, Various Purpose, GO, 5.25%, 12/01/22 (d)    5,955    6,203,205 
    East Side Union High School District, California, Santa Clara County,         
    GO (Election of 2002), Series B, 5%, 8/01/27 (e)        1,800    1,763,262 
    Modesto, California, Schools Infrastructure Financing Agency, Special         
    Tax Bonds, 5.50%, 9/01/36 (c)        2,565    2,568,796 
    Rancho Cucamonga, California, Redevelopment Agency, Tax Allocation         
    Refunding Bonds (Rancho Redevelopment Project),             
    Series A, 5%, 9/01/34 (b)        1,000    963,280 
    San Pablo, California, Joint Powers Financing Authority, Tax         
    Allocation Revenue Refunding Bonds, 5.659%, 12/01/24 (b)(f)    2,635    1,053,895 
    San Pablo, California, Joint Powers Financing Authority, Tax         
    Allocation Revenue Refunding Bonds, 5.66%, 12/01/25 (b)(f)    2,355    884,538 
    San Pablo, California, Joint Powers Financing Authority, Tax Allocation         
    Revenue Refunding Bonds, 5.661%, 12/01/26 (b)(f)        2,355    829,996 
    Santa Ana, California, Unified School District, GO, 5%, 8/01/32 (b)    4,265    4,206,356 
    Stockton, California, Public Financing Revenue Bonds             
    (Redevelopment Projects), Series A, 5.25%, 9/01/31 (g)    2,140    1,965,719 
    Vista, California, COP (Community Projects), 5%, 5/01/37 (b)    3,600    3,487,680 
    West Contra Costa, California, Unified School District, GO, Series C,         
    5%, 8/01/21 (e)        3,480    3,531,608 
               
                29,433,795 
 
 
 
 
Colorado - 6.9%    Aurora, Colorado, COP, 5.75%, 12/01/10 (c)(h)        10,620    11,435,510 
 
 
 
 
District of Columbia -    District of Columbia, Deed Tax Revenue Bonds (Housing Production Trust         
0.9%    Fund - New Communities Project), Series A, 5%, 6/01/32 (b)    1,500    1,471,230 
 
 
 
Florida - 26.6%    Brevard County, Florida, Health Facilities Authority, Healthcare Facilities         
    Revenue Bonds (Health First Inc. Project), 5%, 4/01/34        1,650    1,493,068 
    Broward County, Florida, HFA, S/F Mortgage Revenue Refunding Bonds,         
    AMT, Series E, 5.90%, 10/01/39 (i)(j)        1,470    1,470,073 
    Broward County, Florida, School Board, COP, Series A,             
    5.25%, 7/01/33 (d)        3,300    3,277,164 
 
 
 
 
Portfolio Abbreviations                 
 
 
 
 

To simplify the listings of portfolio holdings in the Schedule of Investments, the names of many of the securities have been abbreviated according to the list below.

AMT    Alternative Minimum Tax (subject to)    IDA    Industrial Development Authority 
COP    Certificates of Participation    M/F    Multi-Family 
EDA    Economic Development Authority    PCR    Pollution Control Revenue Bonds 
GO    General Obligation Bonds    S/F    Single-Family 
HDA    Housing Development Authority    VRDN    Variable Rate Demand Notes 
HFA    Housing Finance Agency         

1

BlackRock MuniHoldings Insured Fund, Inc.             
Schedule of Investments July 31, 2008 (Unaudited)    (Percentages shown are based on Net Assets) 
 
            Par     
State    Municipal Bonds        (000)         Value 
 
 
 
 
    Hillsborough County, Florida, HFA, S/F Mortgage Revenue Bonds, AMT,         
    Series 1, 5.375%, 10/01/49 (i)(j)    $ 2,100    $ 1,995,042 
    Hillsborough County, Florida, IDA, Hospital Revenue Bonds (H. Lee Moffitt         
    Cancer Center Project), Series A, 5.25%, 7/01/37        2,450    2,281,440 
    Hillsborough County, Florida, IDA, PCR, Refunding (Tampa Electric         
    Company Project), Series B, 5.15%, 9/01/25        700    709,961 
    Lee Memorial Health System, Florida, Hospital Revenue Bonds,         
    Series A, 5%, 4/01/32 (c)        3,000    2,894,880 
    Miami-Dade County, Florida, Aviation Revenue Refunding Bonds (Miami         
    International Airport), AMT, Series A, 5.50%, 10/01/41 (d)    3,900    3,858,582 
    Miami-Dade County, Florida, School Board, COP, Refunding, Series B,         
    5.25%, 5/01/26 (k)        5,000    5,087,400 
    Miami-Dade County, Florida, School Board, COP, Refunding, Series B,         
    5.25%, 5/01/31 (k)        2,400    2,414,352 
    Miami-Dade County, Florida, School Board, COP, Series A,         
    5%, 5/01/21 (d)(e)        2,385    2,436,874 
    Miami-Dade County, Florida, Special Obligation Revenue Bonds,         
    Sub-Series A, 5.24%, 10/01/37 (b)(f)        2,225    395,382 
    Miami, Florida, Special Obligation Revenue Bonds (Street and Sidewalk         
    Improvement Program), 5%, 1/01/37 (b)        2,000    1,895,460 
    Okaloosa County, Florida, Water and Sewer Revenue Refunding         
    Bonds, 5%, 7/01/36 (d)        1,000    998,460 
    Orange County, Florida, Health Facilities Authority, Hospital Revenue         
    Bonds (Orlando Regional Healthcare), VRDN, Series A-1,         
    2.50%, 10/01/41 (d)(l)        3,300    3,300,000 
    Orlando, Florida, Senior Tourist Development Tax Revenue Bonds         
    (6th Cent Contract Payments), Series A, 5.25%, 11/01/38 (k)    2,000    1,972,960 
    Pasco County, Florida, Half-Cent Sales Tax Revenue Bonds,         
    5.125%, 12/01/28 (c)        3,850    3,864,861 
    Seminole County, Florida, Water and Sewer Revenue Bonds,         
    5%, 10/01/31        3,750    3,774,750 
               
                44,120,709 
 
 
 
 
Illinois - 6.4%    Chicago, Illinois, GO, Series A, 6%, 7/01/10 (e)(h)        2,790    3,008,569 
    Chicago, Illinois, O'Hare International Airport, General Airport Revenue         
    Refunding Bonds, Third Lien, AMT, Series A,             
    5.75%, 1/01/19 (b)        1,875    1,882,950 
    Chicago, Illinois, O'Hare International Airport Revenue Bonds,         
    Third Lien, Series A, 5%, 1/01/31 (b)        1,000    944,590 
    Illinois State, GO, First Series, 6%, 1/01/18 (e)        4,500    4,666,680 
    Lake, Cook, Kane and McHenry Counties, Illinois, Community Unit         
    School District Number 220, GO, 5.75%, 12/01/19 (e)        45    47,434 
               
                10,550,223 
 
 
 
 
Indiana - 6.0%    Indiana Municipal Power Agency, Power Supply System Revenue         
    Bonds, Series A, 5%, 1/01/37 (b)        4,460    4,258,140 
    Indiana Municipal Power Agency, Power Supply System Revenue         
    Bonds, Series A, 5%, 1/01/42 (b)        6,000    5,687,820 
               
                9,945,960 
 
 
 
 

2

BlackRock MuniHoldings Insured Fund, Inc.             
Schedule of Investments July 31, 2008 (Unaudited)    (Percentages shown are based on Net Assets) 
 
            Par     
State    Municipal Bonds        (000)         Value 
 
 
 
 
Louisiana - 0.6%    Louisiana State Gas and Fuels Tax Revenue Bonds, Series A,         
    5%, 5/01/41 (e)        $ 940    $ 913,379 
 
 
 
 
Massachusetts - 1.8%    Massachusetts State, HFA, Housing Development Revenue Refunding         
    Bonds, AMT, Series A, 5.15%, 6/01/11 (b)        565    571,164 
    Massachusetts State, HFA, Rental Housing Mortgage Revenue Bonds,         
    AMT, Series C, 5.50%, 7/01/32 (d)        2,440    2,470,695 
               
                3,041,859 
 
 
 
 
Michigan - 3.9%    Michigan State Strategic Fund, Limited Obligation Revenue Refunding         
    Bonds (Detroit Edison Company Pollution Control Project), AMT,         
    Series A, 5.50%, 6/01/30 (m)        2,000    1,824,640 
    Michigan State Strategic Fund, Limited Obligation Revenue Refunding         
    Bonds (Detroit Edison Company Pollution Control Project), AMT,         
    Series B, 5.65%, 9/01/29 (m)        1,500    1,485,345 
    Michigan State Strategic Fund, Limited Obligation Revenue Refunding         
    Bonds (Detroit Edison Company Pollution Control Project), AMT,         
    Series C, 5.65%, 9/01/29 (m)        3,500    3,190,775 
               
                6,500,760 
 
 
 
 
Minnesota - 2.6%    Sauk Rapids, Minnesota, Independent School District Number 47, GO,         
    Series A, 5.65%, 2/01/19 (b)        4,015    4,285,009 
 
 
 
 
Missouri - 5.6%    Cape Girardeau, Missouri, School District Number 063, GO         
    (Missouri Direct Deposit Program), 5.50%, 3/01/18 (e)        2,000    2,093,620 
    Mehlville, Montana, School District Number R-9, COP, Series A, 5.50%,         
    3/01/11 (d)(h)        5,510    5,902,918 
    Mehlville, Montana, School District Number R-9, COP, Series A, 5.50%,         
    3/01/14 (d)        360    378,781 
    Mehlville, Montana, School District Number R-9, COP, Series A, 5.50%,         
    3/01/15 (d)        405    426,129 
    Mehlville, Montana, School District Number R-9, COP, Series A, 5.50%,         
    3/01/16 (d)        215    226,216 
    Mehlville, Montana, School District Number R-9, COP, Series A, 5.50%,         
    3/01/17 (d)        280    294,608 
               
                9,322,272 
 
 
 
 
Nevada - 1.0%    Clark County, Nevada, Passenger Facility Charge Revenue Bonds (Las         
    Vegas McCarran International), AMT, Series A-1, 5%, 7/01/23 (c)(d)    1,750    1,654,835 
 
 
 
New Jersey - 6.4%    New Jersey EDA, Cigarette Tax Revenue Bonds, 5.75%, 6/15/34 (k)    3,800    3,894,696 
    New Jersey EDA, Motor Vehicle Surcharge Revenue Bonds, Series A,         
    5.25%, 7/01/33 (b)        6,700    6,791,455 
               
                10,686,151 
 
 
 
 
New York - 9.7%    Nassau Health Care Corporation, New York, Health System Revenue         
    Bonds, 5.75%, 8/01/09 (d)(h)        7,130    7,562,934 
    New York City, New York, GO, Series E, 5%, 11/01/17 (d)    4,000    4,233,560 
    New York City, New York, Sales Tax Asset Receivable Corporation         
    Revenue Bonds, Series A, 5.25%, 10/15/27 (c)        4,095    4,239,226 
               
                16,035,720 
 
 
 
 
Oregon - 0.9%    Portland, Oregon, Urban Renewal and Redevelopment Tax Allocation         
    Bonds (Oregon Convention Center), Series A, 5.75%, 6/15/15 (c)    1,400    1,458,940 
 
 
 

3

BlackRock MuniHoldings Insured Fund, Inc.             
Schedule of Investments July 31, 2008 (Unaudited)    (Percentages shown are based on Net Assets) 
 
            Par     
State    Municipal Bonds        (000)         Value 
 
 
 
 
Rhode Island - 4.9%    Providence, Rhode Island, Redevelopment Agency Revenue Refunding         
    Bonds (Public Safety and Municipal Buildings), Series A, 5.75%,         
    4/01/10 (c)(h)    $ 5,000    $ 5,336,100 
    Rhode Island State Health and Educational Building Corporation Revenue         
    Bonds (Rhode Island School of Design), Series D, 5.50%,             
    8/15/31 (m)        2,870    2,869,914 
               
                8,206,014 
 
 
 
 
South Carolina - 0.9%    Medical University Hospital Authority, South Carolina, Hospital Facilities         
    Revenue Refunding Bonds, Series A, 5.25%, 2/15/25 (a)(b)        1,525    1,550,986 
 
 
 
 
Tennessee - 2.6%    Tennessee HDA, Revenue Refunding Bonds (Homeownership Program),         
    AMT, Series A, 5.25%, 7/01/22 (d)        2,300    2,266,443 
    Tennessee HDA, Revenue Refunding Bonds (Homeownership Program),         
    AMT, Series A, 5.35%, 1/01/26 (d)        2,115    2,029,300 
               
                4,295,743 
 
 
 
 
Texas - 19.6%    Dallas-Fort Worth, Texas, International Airport, Joint Revenue Bonds,         
    AMT, Series B, 6%, 11/01/23 (b)        700    702,758 
    Dallas-Fort Worth, Texas, International Airport Revenue Bonds, AMT,         
    Series A, 5.50%, 11/01/33 (b)        8,000    7,591,840 
    Harris County, Texas, Health Facilities Development Corporation,         
    Hospital Revenue Bonds (Methodist Hospital Project), VRDN, Series C,         
    2.30%, 12/01/41 (d)(l)        1,600    1,600,000 
    Houston, Texas, Community College System, Participation Interests, COP         
    (Alief Center Project), 5.75%, 8/15/22 (b)        2,595    2,661,148 
    North Texas Tollway Authority, System Revenue Refunding Bonds,         
    First Tier, 5.75%, 1/01/40 (b)        6,710    6,851,447 
    North Texas Tollway Authority, System Revenue Refunding Bonds,         
    First Tier, Series B, 5.75%, 1/01/40 (b)        6,275    6,407,277 
    North Texas Tollway Authority, System Revenue Refunding Bonds,         
    Series A, 5.625%, 1/01/33 (b)        6,585    6,688,055 
               
                32,502,525 
 
 
 
 
Washington - 2.5%    Chelan County, Washington, Public Utility District Number 001,         
    Consolidated Revenue Bonds (Chelan Hydro System), AMT, Series A,         
    5.45%, 7/01/37 (c)        2,310    2,188,494 
    Snohomish County, Washington, Public Utility District Number 001,         
    Electric Revenue Bonds, 5.50%, 12/01/22 (d)        1,810    1,918,401 
               
                4,106,895 
 
 
 
 
Wisconsin - 0.3%    Wisconsin State Health and Educational Facilities Authority Revenue         
    Bonds (Blood Center of Southeastern Wisconsin Project),             
    5.50%, 6/01/24        500    501,195 
 
 
 
 
Puerto Rico - 1.1%    Puerto Rico Public Buildings Authority, Government Facilities Revenue         
    Refunding Bonds, Series D, 5.25%, 7/01/36        1,870    1,824,428 
 
 
 
 
    Total Municipal Bonds - 134.6%            223,337,120 
 
 
 
 
    Municipal Bonds Transferred to             
    Tender Option Bond Trusts (n)             
 
 
 
 
California - 10.2%    Palomar Pomerado Health Care District, California, GO             
    (Election of 2004), Series A, 5.125%, 8/01/37 (b)        4,335    4,370,364 

4

BlackRock MuniHoldings Insured Fund, Inc.             
Schedule of Investments July 31, 2008 (Unaudited)    (Percentages shown are based on Net Assets) 
 
    Municipal Bonds Transferred to                             Par     
State    Tender Option Bond Trusts (n)                       (000)         Value 
 
 
 
 
    Sacramento County, California, Airport System Revenue Bonds,         
    AMT, Senior Series B, 5.25%, 7/01/39 (d)        $ 3,149    $ 3,014,411 
    San Jose, California, GO (Libraries, Parks and Public Safety Projects),         
    5%, 9/01/30 (b)                       1,258    1,266,271 
    Sequoia, California, Unified High School District, GO, Refunding,         
    Series B, 5.50%, 7/01/35 (d)                       3,149    3,301,517 
    Tustin, California, Unified School District, Senior Lien Special Tax         
    Bonds (Community Facilities District Number 97-1),             
    Series A, 5%, 9/01/32 (d)                       2,180    2,181,504 
    Tustin, California, Unified School District, Senior Lien Special Tax         
    Bonds (Community Facilities District Number 97-1),             
    Series A, 5%, 9/01/38 (d)                       2,800    2,774,072 
               
                16,908,139 
 
 
 
 
Colorado - 3.4%    Colorado Health Facilities Authority Revenue Bonds (Catholic Health),         
    Series C-3, 5.10%, 10/01/41 (d)                     5,609     5,555,723 
 
 
 
 
Florida - 6.8%    Jacksonville, Florida, Health Facilities Authority, Hospital Revenue         
    Bonds (Baptist Medical Center Project), 5%, 8/15/37 (d)                   4,515    4,426,777 
    Lee County, Florida, HFA, S/F Mortgage Revenue Bonds         
    (Multi-County Program), AMT, Series A-2, 6%, 9/01/40 (i)(j)                   2,505    2,565,396 
    Saint Petersburg, Florida, Public Utilities Revenue Refunding Bonds,         
    5%, 10/01/35 (b)                       4,303    4,252,251 
               
                11,244,424 
 
 
 
 
Georgia - 2.5%    Augusta, Georgia, Water and Sewer Revenue Bonds,             
    5.25%, 10/01/34 (d)                       3,997    4,112,545 
 
 
 
 
Illinois - 6.2%    Chicago, Illinois, O'Hare International Airport, General Airport         
    Revenue Refunding Bonds, Third Lien, AMT, Series A, 5%, 1/01/38 (d)                   8,000    7,812,480 
    Chicago, Illinois, Water Revenue Refunding Bonds, Second Lien,         
    5.25%, 11/01/33 (d)                       2,503    2,550,940 
               
                10,363,420 
 
 
 
 
Massachusetts - 6.9%    Massachusetts Bay Transportation Authority, Sales Tax Revenue         
    Refunding Bonds, Senior Series A, 5%, 7/01/35                       3,375    3,376,687 
    Massachusetts State School Building Authority, Dedicated Sales Tax         
    Revenue Bonds, Series A, 5%, 8/15/30 (d)                       7,998    8,058,782 
               
                11,435,469 
 
 
 
 
New Jersey - 3.3%    New Jersey State Turnpike Authority, Turnpike Revenue Bonds,         
    Series C, 5%, 1/01/30 (d)                       5,487    5,537,500 
 
 
 
 
Virginia - 0.9%    Virginia State, HDA, Commonwealth Mortgage Revenue Bonds,         
    Series H, Sub-Series H-1, 5.35%, 7/01/31 (b)                       1,500    1,511,265 
 
 
 
 
Washington - 2.5%    Bellevue, Washington, GO, Refunding, 5.50%, 12/01/39 (b)                   3,995    4,099,655 
 
 
 
    Total Municipal Bonds Transferred to Tender             
    Option Bond Trusts - 42.7%            70,768,140 
 
 
 
 
    Total Long-Term Investments (Cost - $298,786,002) - 177.3%        294,105,260 
 
 
 

5

BlackRock MuniHoldings Insured Fund, Inc.         
Schedule of Investments July 31, 2008 (Unaudited)    (Percentages shown are based on Net Assets) 
 
                                                                 Short-Term Securities    Shares    Value 
 
 
                                                                 Merrill Lynch Institutional Tax-Exempt Fund, 2.08% (o)(p)    9,720,732    $ 9,720,732 
 
 
                                                                 Total Short-Term Securities (Cost - $9,720,732) - 5.9%        9,720,732 
 
 
                                                                 Total Investments (Cost - $308,506,734*) - 183.2%        303,825,992 
                                                                 Other Assets Less Liabilities - 1.6%        2,707,544 
                                                                 Liability for Trust Certificates, Including Interest         
                                                                 Expense and Fees Payable - (28.0)%        (46,415,769) 
                                                                 Preferred Stock, at Redemption Value - (56.8)%        (94,246,184) 
   
 
                                                                 Net Assets Applicable to Common Stock - 100.0%    $ 165,871,583 
   

*      The cost and unrealized appreciation (depreciation) of investments as of July 31, 2008, as computed for federal income tax purposes, were as follows:
 
Aggregate cost    $ 261,401,431 
   
Gross unrealized appreciation    $ 3,179,773 
Gross unrealized depreciation    (7,023,620) 
   
Net unrealized depreciation    $ (3,843,847) 
   

(a)      FHA Insured.
 
(b)      MBIA Insured.
 
(c)      AMBAC Insured.
 
(d)      FSA Insured.
 
(e)      FGIC Insured.
 
(f)      Represents a zero coupon bond. Rate shown reflects the effective yield at time of purchase.
 
(g)      Radian Insured.
 
(h)      U.S. government securities, held in escrow, are used to pay interest on this security, as well as to retire the bond in full at the date indicated, typically at a premium to par.
 
(i)      FHLMC Collateralized.
 
(j)      FNMA/GNMA Collateralized.
 
(k)      Assured Guaranty Insured.
 
(l)      Variable rate security. Rate shown is as of report date. Maturity shown is the final maturity date.
 
(m)      XL Capital Insured.
 
(n)      Securities represents bonds transferred to a tender option bond trust in exchange for which the Fund acquired residual interest certificates. These securities serve as collateral in a financing transaction.
 
(o)      Investments in companies considered to be an affiliate of the Fund, for purposes of Section 2(a)(3) of the Investment Company Act of 1940, were as follows:
 
        Net     
    Affiliate    Activity    Income 
   
 
 
    Merrill Lynch Institutional Tax-Exempt Fund    9,699,911    $ 36,783 
   
 
 
(p)    Represents the current yield as of report date.         

6

BlackRock MuniHoldings Insured Fund, Inc.

Schedule of Investments as of July 31, 2008 (Unaudited)

The inputs or methodology used for valuing securities are not necessarily an indication of the risk associated with investing in those securities. For information about the Fund's policy regarding valuation of investments and other significant accounting policies, please refer to the Fund's most recent financial statements as contained in its annual report.

The following table summarizes the inputs used as of July 31, 2008 in determining the fair valuation of the Fund's investments:

Valuation    Investments in 
Inputs    Securities 
 
Level 1    $ 9,720,732 
Level 2    294,105,260 
Level 3    - 
 
Total    $ 303,825,992 
   

7

Item 2 – Controls and Procedures

2(a) – The registrant’s principal executive and principal financial officers or persons performing
similar functions have concluded that the registrant’s disclosure controls and procedures (as
defined in Rule 30a-3(c) under the Investment Company Act of 1940, as amended (the
“1940 Act”)) are effective as of a date within 90 days of the filing of this report based on the
evaluation of these controls and procedures required by Rule 30a-3(b) under the 1940 Act
and Rule 13a-15(b) under the Securities Exchange Act of 1934, as amended.

2(b) – There were no changes in the registrant’s internal control over financial reporting (as
defined in Rule 30a-3(d) under the 1940 Act) that occurred during the registrant’s last fiscal
quarter that have materially affected, or are reasonably likely to materially affect, the
registrant’s internal control over financial reporting.

Item 3 – Exhibits

Certifications – Attached hereto

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment
Company Act of 1940, the registrant has duly caused this report to be signed on its behalf by
the undersigned, thereunto duly authorized.

BlackRock MuniHoldings Insured Fund, Inc.

By: /s/ Donald C. Burke
Donald C. Burke
Chief Executive Officer of
BlackRock MuniHoldings Insured Fund, Inc.

Date: September 19, 2008

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment
Company Act of 1940, this report has been signed below by the following persons on behalf
of the registrant and in the capacities and on the dates indicated.

By: /s/ Donald C. Burke
Donald C. Burke
Chief Executive Officer (principal executive officer) of
BlackRock MuniHoldings Insured Fund, Inc.

Date: September 19, 2008

By: /s/ Neal J. Andrews
Neal J. Andrews
Chief Financial Officer (principal financial officer) of
BlackRock MuniHoldings Insured Fund, Inc.

Date: September 19, 2008