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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                    FORM 8-K

                                 CURRENT REPORT

                       PURSUANT TO SECTION 13 OR 15(d) OF
                       THE SECURITIES EXCHANGE ACT OF 1934

                DATE OF REPORT (DATE OF EARLIEST EVENT REPORTED):
                                FEBRUARY 1, 2006

                               TRANSGENOMIC, INC.
             (Exact name of registrant as specified in its charter)

               Delaware                                  000-30975
         (State of Formation)                    (Commission File Number)

                                    911789357
                      (IRS Employer Identification Number)

            12325 Emmet Street
                Omaha, NE                                 68164
(Address of principal executive offices)                (Zip Code)

                                 (402) 452-5400
              (Registrants' telephone number, including area code)

                                 Not applicable
          (Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions:

[ ]  Written communications pursuant to Rule 425 under the Securities
     Act (17 CFR 230.425)

[ ]  Soliciting material pursuant to Rule 14a-12 under the Exchange
     Act (17 CFR 240.14a-12)

[ ]  Pre-commencement communications pursuant to Rule 14d-2(b) under the
     Exchange Act (17 CFR 240.14d-2(b))

[ ]  Pre-commencement communications pursuant to Rule 13e-4(c) under the
     Exchange Act (17 CFR 240.13e(c))

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ITEM 8.01  OTHER EVENTS.

        On Wednesday, February 1, 2006, the Company issued a press release
announcing the use of its WAVE(R) System and Surveyor(TM) Nuclease to detect
mutations associated with response to therapy in lung cancer. A copy of the
press release is filed herewith as Item 9.01 and is incorporated herein by
reference.

ITEM 9.01  FINANCIAL STATEMENTS AND EXHIBITS.

        Press Release, dated February 1, 2006, announcing the use of the
Company's WAVE System and Surveyor Nuclease to detect mutations associated with
response to therapy in lung cancer.

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                                   SIGNATURES

        Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                                   TRANSGENOMIC, INC.


                                                   By  /s/ Mitchell L. Murphy
                                                       -------------------------
                                                       Mitchell L. Murphy
                                                       VP, Secretary & Treasurer

February 1, 2006

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