Unassociated Document

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549

FORM 10-Q
 
(Mark One)
x
QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934
   
FOR THE QUARTERLY PERIOD ENDED September 30, 2008
 
 
or
   
o
TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934
   
FOR THE TRANSITION PERIOD FROM ________ TO ________.
 
COMMISSION FILE NUMBER 333-61610

BRAINSTORM CELL THERAPEUTICS INC.

(Exact name of registrant as specified in its charter)
 
DELAWARE
20-8133057
(State or other jurisdiction of
(I.R.S. Employer
incorporation or organization)
Identification No.)
 
110 EAST 59th STREET
NEW YORK, NY 10022
(Address of principal executive offices)

(212) 557-9000
(Registrant's telephone number)

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the past 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes x No o
 
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the definitions of “large accelerated filer,” “accelerated filer” and “smaller reporting company” in Rule 12b-2 of the Exchange Act.

Large accelerated filer  ¨            
Accelerated filer  ¨              
Non-accelerated filer  ¨ (Do not check if a smaller reporting company)
Smaller reporting company  x
 
Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).
Yes o No x

As of November 3, 2008, the number of shares outstanding of the registrant’s common stock, $0.00005 par value per share, was 55,241,418
 

 
TABLE OF CONTENTS
 
 
 
Page
Number
PART I
 
 
 
 
 
Item 1. Financial Statements
 
1
Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations
 
21
Item 3. Quantitative and Qualitative Disclosures About Market Risk
 
25
Item 4T. Controls and Procedures
 
26
 
 
 
PART II
 
 
 
 
27
Item 1. Legal Proceedings
 
27
Item 1A. Risk Factors
 
28
Item 5. Other Information
 
28
Item 6. Exhibits
 
28
 


 
PART I: FINANCIAL INFORMATION

SPECIAL NOTE
 
Unless otherwise specified in this Quarterly Report on Form 10-Q, all references to currency, monetary values and dollars set forth herein shall mean United States (U.S.) dollars.
 
Item 1. Financial Statements. 



BRAINSTORM CELL THERAPEUTICS INC. AND SUBSIDIARY
(A development stage Company)

INTERIM CONSOLIDATED FINANCIAL STATEMENTS

AS OF SEPTEMBER 30, 2008

IN U.S. DOLLARS IN THOUSANDS

UNAUDITED

INDEX

 
Page
   
Consolidated Balance Sheets
2
 
 
Consolidated Statements of Operations
3
   
Statements of Changes in Stockholders' Equity (Deficiency)
4 - 6
   
Consolidated Statements of Cash Flows
7
   
Notes to Consolidated Financial Statements
7 - 20
 
1


BRAINSTORM CELL THERAPEUTICS INC. AND SUBSIDIARY
(A development stage company)
CONSOLIDATED BALANCE SHEETS
In U.S. dollars in thousands (except share and per share data)

   
September 30,
 
December 31,
 
   
2 0 0 8
 
2 0 0 7
 
   
Unaudited
     
ASSETS
         
CURRENT ASSETS:
         
Cash and cash equivalents
 
$
21
 
$
86
 
Restricted cash
   
40
   
35
 
Other receivable and prepaid expenses
   
87
   
137
 
Total current assets
   
148
   
258
 
               
LONG-TERM INVESTMENTS:
             
Prepaid expenses
   
12
   
9
 
Severance pay fund
   
109
   
75
 
Total Long-term investments
   
121
   
84
 
               
PROPERTY AND EQUIPMENT, NET
   
783
   
739
 
               
Deferred Charges
   
-
   
2
 
Total assets
   
1,052
   
1,083
 
               
LIABILITIES AND STOCKHOLDERS' DEFICIENCY
             
               
CURRENT LIABILITIES:
             
Short term credit from bank
   
95
   
-
 
Trade payables
   
737
   
838
 
Other accounts payable and accrued expenses
   
1,505
   
1,049
 
Short-term convertible loans
   
169
   
396
 
Short-term loan
   
197
   
945
 
Total current liabilities
   
2,703
   
3,228
 
               
LONG TERM CONVERTIBLE LOANS
   
-
   
200
 
               
ACCRUED SEVERANCE PAY
   
136
   
83
 
Total liabilities
   
2,839
   
3,511
 
               
STOCKHOLDERS' DEFICIENCY:
             
Stock capital: (Note 7)
             
Common stock of $0.00005 par value - Authorized: 800,000,000 shares at September 30, 2008 and December 31, 2007; Issued and outstanding: 55,241,418 and 41,004,409 shares at September 30, 2008 and December 31, 2007, respectively
   
3
   
2
 
Subscription on account of shares
   
133
   
-
 
Additional paid-in capital
   
33,411
   
30,058
 
Deficit accumulated during the development stage
   
(35,334
)
 
(32,488
)
Total stockholders' deficiency
   
(1,787
)
 
(2,428
)
               
Total liabilities and stockholders' deficiency
 
$
1,052
 
$
1,083
 
 
The accompanying notes are an integral part of the consolidated financial statements.

2



BRAINSTORM CELL THERAPEUTICS INC. AND SUBSIDIARY
(A development stage company)
CONSOLIDATED STATEMENTS OF OPERATIONS
In U.S. dollars in thousands (except share data)

   
Three months ended
September 30,
 
Nine months ended
September 30,
 
Period from September 22, 2000 (inception date) through September 30,
 
   
2 0 0 8
 
2 0 0 7
 
2 0 0 8
 
2 0 0 7
 
2 0 0 8
 
   
Unaudited
 
Unaudited
 
Unaudited
 
Operating costs and expenses:
                     
Research and development
 
$
455
 
$
524
 
$
1,623
 
$
1,520
 
$
21,828
 
Less- participation by the Office of the Chief scientist
   
163
   
198
   
458
   
198
   
798
 
                                 
Research and development, net
   
292
   
326
   
1,165
   
1,322
   
21,030
 
General and administrative
   
405
   
865
   
1,428
   
2,070
   
11,488
 
                                 
Totaloperating costs and expenses
   
697
   
1,191
   
2,593
   
3,392
   
32,518
 
                                 
Financial expenses, net
   
31
   
266
   
253
   
930
   
2,599
 
                                 
     
728
   
1,457
   
2,846
   
4,322
   
35,117
 
Taxes on income
   
-
   
5
   
-
   
16
   
53
 
                                 
Loss from continuing operations
   
728
   
1,462
   
2,846
   
4,338
   
35,170
 
Net loss from discontinued operations
   
-
   
-
   
-
   
-
   
164
 
                                 
Net loss
 
$
728
 
$
1,462
 
$
2,846
 
$
4,338
 
$
35,334
 
                                 
Basic and diluted net loss per share from continuing operations
   
0.01
   
0.05
   
0.06
   
0.16
       
Weighted average number of shares outstanding used in computing basic and diluted net loss per share
   
51,354,951
   
29,868,357
   
46,958,440
   
26,373,349
   
 
The accompanying notes are an integral part of the consolidated financial statements.

3

 
BRAINSTORM CELL THERAPEUTICS INC. AND SUBSIDIARY
(A development stage company)
STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY (DEFICIENCY)
In U.S. dollars in thousands (except share data)

               
Deficit accumulated
 
Total
 
       
Additional
 
Deferred
 
during the
 
stockholders'
 
   
Common stock
 
paid-in
 
stock-based
 
development
 
equity
 
   
Number
 
Amount
 
capital
 
compensation
 
stage
 
(deficiency)
 
Balance as of September 22, 2000 (date of inception)
   
-
   
-
   
-
   
-
   
-
   
-
 
                                       
Stock issued on September 22, 2000 for cash at $0.00188 per share
   
8,500,000
 
$
1
 
$
16
 
$
-
 
$
-
 
$
17
 
Stock issued on March 31, 2001 for cash at $0.0375 per share
   
1,600,000
   
(*) -
   
60
   
-
   
-
   
60
 
Contribution of capital
   
-
   
-
   
8
   
-
   
-
   
8
 
Net loss
   
-
   
-
   
-
   
-
   
(17
)
 
(17
)
 
                                     
Balance as of March 31, 2001
   
10,100,000
   
1
   
84
   
-
   
(17
)
 
68
 
                                       
Contribution of capital
   
-
   
-
   
11
   
-
   
-
   
11
 
Net loss
   
-
   
-
   
-
   
-
   
(26
)
 
(26
)
 
                                     
Balance as of March 31, 2002
   
10,100,000
   
1
   
95
   
-
   
(43
)
 
53
 
                                       
Contribution of capital
   
-
   
-
   
15
   
-
   
-
   
15
 
Net loss
   
-
   
-
   
-
   
-
   
(47
)
 
(47
)
                                       
Balance as of March 31, 2003
   
10,100,000
   
1
   
110
   
-
   
(90
)
 
21
 
                                       
2-for-1 stock split
   
10,100,000
   
(*)-
   
-
   
-
   
-
   
-
 
Stock issued on August 31, 2003 to purchase mineral option at $0.065 per share
   
100,000
   
(*)-
   
6
   
-
   
-
   
6
 
Cancellation of shares granted to Company's President
   
(10,062,000
)
 
(*)-
   
(*) -
   
-
   
-
   
-
 
Contribution of capital
   
-
   
-
   
15
   
-
   
-
   
15
 
Net loss
   
-
   
-
   
-
   
-
   
(73
)
 
(73
)
 
                                     
Balance as of March 31, 2004
   
10,238,000
   
1
   
131
   
-
   
(163
)
 
(31
)
                                       
Stock issued on June 24, 2004 for private placement at $0.01 per share, net of $25,000 issuance expenses
   
8,510,000
   
(*)-
   
60
   
-
   
-
   
60
 
Contribution capital
   
-
   
-
   
7
   
-
   
-
   
7
 
Stock issued in 2004 for private placement at $0.75 per unit
   
1,894,808
   
(*)-
   
1,418
   
-
   
-
   
1,418
 
Cancellation of shares granted to service providers
   
(1,800,000
)
 
(*)-
         
-
   
-
   
-
 
Deferred stock-based compensation related to options granted to employees
   
-
   
-
   
5,979
   
(5,979
)
 
-
   
-
 
Amortization of deferred stock-based compensation related to shares and options granted to employees
   
-
   
-
   
-
   
584
   
-
   
584
 
Compensation related to shares and options granted to service providers
   
2,025,000
   
(*)-
   
17,506
   
-
   
-
   
17,506
 
Net loss
   
-
   
-
   
-
   
-
   
(18,840
)
 
(18,840
)
Balance as of March 31, 2005
   
20,867,808
 
$
1
 
$
25,101
 
$
(5,395
)
$
(19,003
)
$
704
 
 
 (*) Represents an amount less than $1.
The accompanying notes are an integral part of the consolidated financial statements.

4


BRAINSTORM CELL THERAPEUTICS INC. AND SUBSIDIARY
(A development stage company)
STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY (DEFICIENCY)
U.S. dollars in thousands (except share data)

               
Deficit accumulated
 
Total
 
       
Additional
 
Deferred
 
during the
 
stockholders'
 
   
Common stock
 
paid-in
 
stock-based
 
development
 
equity
 
   
Number
 
capital
 
compensation
 
stage
 
(deficiency)
 
(deficiency)
 
                           
Balance as of March 31, 2005
   
20,867,808
 
$
1
 
$
25,101
 
$
(5,395
)
$
(19,003
)
$
704
 
                                       
Stock issued on May 12, 2005 for private placement at $0.8 per share
   
186,875
   
(*) -
   
149
   
-
   
-
   
149
 
Stock issued on July 27, 2005 for private placement at $0.6 per share
   
165,000
   
(*) -
   
99
   
-
   
-
   
99
 
Stock issued on September 30, 2005 for private placement at $0.8 per share
   
312,500
   
(*) -
   
225
   
-
   
-
   
225
 
Stock issued on December 7, 2005 for private placement at $0.8 per share
   
187,500
   
(*) -
   
135
   
-
   
-
   
135
 
Forfeiture of options granted to employees
   
-
   
-
   
(3,363
)
 
3,363
   
-
   
-
 
Deferred stock-based compensation related to shares and options granted to directors and employees
   
200,000
   
(*) -
   
486
   
(486
)
 
-
   
-
 
Amortization of deferred stock-based compensation related to options and shares granted to employees and directors
   
-
   
-
   
51
   
1,123
   
-
   
1,174
 
Stock-based compensation related to options and shares granted to service providers
   
934,904
   
(*) -
   
662
   
-
   
-
   
662
 
Reclassification due to application of EITF 00-19
   
-
   
-
   
(7,906
)
             
(7,906
)
Beneficial conversion feature related to a convertible bridge loan
   
-
   
-
   
164
   
-
   
-
   
164
 
Net loss
   
-
   
-
   
-
   
-
   
(3,317
)
 
(3,317
)
                                       
Balance as of March 31, 2006
   
22,854,587
   
1
   
15,803
   
(1,395
)
 
(22,320
)
 
(7,911
)
                                       
Elimination of deferred stock compensation due to implementation of SFAS 123(R)
   
-
   
-
   
(1,395
)
 
1,395
   
-
   
-
 
Stock-based compensation related to shares and options granted to directors and employees
   
200,000
   
-
   
1,168
   
-
   
-
   
1,168
 
Reclassification due to application of EITF 00-19
   
-
   
-
   
7,191
   
-
   
-
   
7,191
 
Stock-based compensation related to options and shares granted to service providers
   
1,147,225
   
(*) -
   
453
   
-
   
-
   
453
 
Warrants issued to convertible note holder
   
-
   
-
   
11
   
-
   
-
   
11
 
Warrants issued to loan holder
   
-
   
-
   
110
   
-
   
-
   
110
 
Beneficial conversion feature related to convertible bridge loans
   
-
   
-
   
1,086
   
-
   
-
   
1,086
 
Net loss
   
-
   
-
   
-
   
-
   
(3,924
)
 
(3,924
)
                                       
Balance as of December 31, 2006
   
24,201,812
 
$
1
 
$
24,427
 
$
-
 
$
(26,244
)
$
(1,816
)
 
(*) Represents an amount less than $1 .
The accompanying notes are an integral part of the consolidated financial statements.

5


BRAINSTORM CELL THERAPEUTICS INC. AND SUBSIDIARY
(A development stage company)
STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY (DEFICIENCY)
U.S. dollars in thousands (except share data)

               
Deficit accumulated
 
Total
 
       
Additional
 
Deferred
 
during the
 
stockholders'
 
   
Common stock
 
paid-in
 
stock-based
 
development
 
equity
 
   
Number
 
Amount
 
Capital and subscription of shares
 
compensation
 
stage
 
(deficiency)
 
                           
Balance as of December 31, 2006
   
24,201,812
 
$
1
 
$
24,427
 
$
-
 
$
(26,244
)
$
(1,816
)
                                       
Stock-based compensation related to options and shares granted to service providers
   
544,095
   
(*) -
   
1,446
   
-
   
-
   
1,446
 
Warrants issued to convertible note holder
   
-
   
-
   
109
   
-
   
-
   
109
 
Stock-based compensation related to shares and options granted to directors and employees
   
200,000
   
(*) -
   
1,232
   
-
   
-
   
1,232
 
Beneficial conversion feature related to convertible loans
   
-
   
-
   
407
   
-
   
-
   
407
 
Conversion of convertible loans
   
725,881
   
(*) -
   
224
   
-
   
-
   
224
 
Exercise of warrants
   
3,832,621
   
(*) -
   
214
   
-
   
-
   
214
 
Stock issued for private placement at $0.1818 per unit, net of finder's fee
   
11,500,000
   
1
   
1,999
   
-
   
-
   
2,000
 
Net loss
   
-
   
-
   
-
   
-
   
(6,244
)
 
(6,244
)
                                       
Balance as of December 31, 2007
   
41,004,409
   
2
   
30,058
   
-
   
(32,488
)
 
(2,428
)
                                       
Stock-based compensation related to options and stock granted to service providers
   
90,000
   
-
   
97
   
-
         
97
 
Stock-based compensation related to stock and options granted to directors and employees
   
-
   
-
   
478
   
-
         
478
 
Beneficial conversion feature related to convertible bridge loans
   
-
   
-
   
-
   
-
             
Conversion of convertible loans
   
3,644,610
   
(*)-
   
1,276
   
-
         
1,276
 
Exercise of warrants
   
1,860,000
   
(*)-
                         
Exercise of options
   
17,399
   
(*)-
   
3
   
-
         
3
 
Stock issued for private placement at $0.1818 per unit, net of finder's fee
   
8,625,000
   
1
   
1,499
               
1,500
 
Subscription of shares
   
-
   
-
   
133
   
-
         
133
 
Net loss
                           
(2,846
)
 
(2,846
)
 
                                     
Balance as of September 30, 2008 (unaudited)
   
55,241,418
 
$
3
 
$
33,544
 
$
-
 
$
(35,334
)
$
(1,787
)

(*) Represents an amount less than $1.
The accompanying notes are an integral part of the consolidated financial statements.

6


BRAINSTORM CELL THERAPEUTICS INC. AND SUBSIDIARY
(A development stage company)
 CONSOLIDATED STATEMENTS OF CASH FLOWS
In U.S. dollars in thousands
 
   
Nine months ended
September 30,
 
Period from September 22, 2000 (inception date) through September 30,
 
   
2 0 0 8
 
2 0 0 7
 
2 0 0 8
 
   
Unaudited
 
Unaudited
 
               
Cash flows from operating activities:
             
               
Net loss
 
$
(2,846
)
$
(4,338
)
$
(35,334
)
Less - loss for the period from discontinued operations
   
-
   
-
   
164
 
Adjustments to reconcile net loss to net cash used in operating activities:
                   
Depreciation and Amortization of deferred charges
   
113
   
126
   
479
 
Erosion of restricted cash
   
(5
)
 
(2
)
 
(11
)
Accrued severance pay, net
   
20
   
7
   
27
 
Accrued interest on loans
   
108
   
(101
)
 
424
 
Amortization of discount on short-term loans
   
42
   
670
   
1,865
 
Change in fair value of options and warrants
   
-
   
-
   
(795
)
Expenses related to stocks and options granted to service providers
   
97
   
1,047
   
20,229
 
Amortization of deferred stock-based compensation related to options granted to employees and directors
   
478
   
970
   
4,636
 
Increase (decrease) in accounts receivable and prepaid expenses
   
49
   
(33
)
 
(87
)
Increase (decrease) in trade payables
   
(101
)
 
(226
)
 
737
 
Increase in other accounts payable and accrued expenses
   
456
   
379
   
1,500
 
Net cash used in continuing operating activities
   
(1,589
)
 
(1,501
)
 
(6,166
)
Net cash used in discontinued operating activities
   
-
   
-
   
(23
)
Total net cash used in operating activities
   
(1,589
)
 
(1,501
)
 
(6,189
)
                     
Cash flows from investing activities:
                   
Purchase of property and equipment
   
(154
)
 
(129
)
 
(1,080
)
Restricted cash
   
(4
)
 
-
   
(29
)
Investment in lease deposit
   
-
   
(4
)
 
(12
)
                     
Net cash used in continuing investing activities
   
(158
)
 
(133
)
 
(1,121
)
Net cash used in discontinued investing activities
   
-
   
-
   
(16
)
Total net cash used in investing activities
   
(158
)
 
(133
)
 
(1,137
)
                     
Cash flows from financing activities:
                   
Proceeds from issuance of common stock and warrants
   
1,634
   
1,250
   
5,721
 
Proceeds from loans, notes and issuance of warrants net
   
-
   
673
   
2,061
 
Credit from the bank
   
95
   
-
   
95
 
Repayment of loans
   
(50
)
 
(133
)
 
(601
)
Proceeds from exercise of warrants and options
   
3
   
25
   
28
 
Net cash provided by continuing financing activities
   
1,682
   
1,815
   
7,304
 
Net cash provided by discontinued financing activities
   
-
   
-
   
43
 
Total net cash provided by financing activities
   
1,682
   
1,815
   
7,347
 
                     
Increase (decrease) in cash and cash equivalents
   
(65
)
 
181
   
21
 
Cash and cash equivalents at the beginning of the period
   
86
   
60
   
-
 
                     
Cash and cash equivalents at end of the period
 
$
21
 
$
241
 
$
21
 
 
The accompanying notes are an integral part of the consolidated financial statements.
 
7


BRAINSTORM CELL THERAPEUTICS INC. AND SUBSIDIARY
(A development stage company)
 
NOTE 1 -
GENERAL
 
a.
Brainstorm Cell Therapeutics Inc. (formerly: Golden Hand Resources Inc.) ("the Company") was incorporated in the State of Washington on September 22, 2000.

b.
On May 21, 2004, the former major stockholders of the Company entered into a purchase agreement with a group of private investors, who purchased from the former major stockholders 6,880,000 shares of the then issued and outstanding 10,238,000 shares of the Company's common stock.

c.
On July 8, 2004, the Company entered into a licensing agreement with Ramot of Tel Aviv University Ltd. ("Ramot"), an Israeli corporation, to acquire certain stem cell technology (see Note 4 to the financial statements as of December 31, 2007). Subsequent to this agreement, the Company decided to focus on the development of novel cell therapies for neurodegenerative diseases, particularly, Parkinson's disease, based on the acquired technology and research to be conducted and funded by the Company.
 
Following the licensing agreement dated July 8, 2004, the management of the Company has decided to abandon all old activities related to the sale of the digital data recorder product. The discontinuation of this activity was accounted for under the provision of SFAS 144, "Accounting for the Impairment or Disposal of Long-Lived Assets".

d.
On November 22, 2004, the Company changed its name from Golden Hand Resources Inc. to Brainstorm Cell Therapeutics Inc. to better reflect its new line of business in the development of novel cell therapies for neurodegenerative diseases.

e.
On October 25, 2004, the Company formed a wholly-owned subsidiary in Israel, Brainstorm Cell Therapeutics Ltd. ("BCT").

f.
On November, 2006, the Company changed its state of incorporation from Washington to Delaware.

g.
On September 17, 2006, the Company's Board determined to change the Company's fiscal year-end from March 31 to December 31.

h.
Since its inception, the Company has devoted substantially most of its efforts to research and development, recruiting management and technical staff, acquiring assets and raising capital. In addition, the Company has not generated revenues. Accordingly, the Company is considered to be in the development stage, as defined in Statement of Financial Accounting Standards No. 7, "Accounting and reporting by development Stage Enterprises" ("SFAS No. 7").
 
8


BRAINSTORM CELL THERAPEUTICS INC. AND SUBSIDIARY
(A development stage company)
 
NOTE 1 -
GENERAL (Cont.)
 
As reflected in the accompanying financial statements, the Company’s operations for the three months ended on September 30, 2008, resulted in a net loss of $ 728,000 and the Company’s balance sheet reflects a net stockholders’ deficiency of $4,043,000. The Company’s ability to continue operating as a “going concern” is dependent on several factors, among them is its ability to raise sufficient additional working capital. Management’s plans in this regard include, among others, raising additional cash from current and potential stockholders and lenders.
 
NOTE 2 -
SIGNIFICANT ACCOUNTING POLICIES

The significant accounting policies applied in the annual financial statements of the Company as of December 31, 2007, are applied consistently in these financial statements.

NOTE 3 -
UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS

The accompanying unaudited interim financial statements have been prepared in a condensed format and include the consolidated financial operations of the Company and its fully owned subsidiary as of September 30, 2008 and for the three months then ended, in accordance with accounting principles generally accepted in the United States relating to the preparation of financial statements for interim periods. Accordingly, they do not include all the information and footnotes required by generally accepted accounting principles for complete financial statements. In the opinion of management, all adjustments (consisting of normal recurring accruals) considered necessary for a fair presentation have been included. Operating results for the three months ended September 30, 2008, are not necessarily indicative of the results that may be expected for the year ended December 31, 2008.

NOTE 4 -
RESEARCH AND LICENSE AGREEMENT

On July 26, 2007, the Company entered into a Second Amended and Restated Research and License Agreement with Ramot. On August 1, 2007, the Company obtained a waiver and release from Ramot pursuant to which Ramot agreed to an amended payment schedule regarding the Company’s payment obligations under the amended license agreement, dated March 30, 2006, and waived all claims against the Company resulting from the Company's previous defaults and non-payment under the original and first amended license agreement. The payments described in the waiver and release covered all payment obligations that were past due and not yet due pursuant to the original license agreement. The waiver and release amends and restates the original payment schedule under the license agreement as follows:

9

BRAINSTORM CELL THERAPEUTICS INC. AND SUBSIDIARY
(A development stage company)

NOTE 4 -
RESEARCH AND LICENSE AGREEMENT (Cont.)

Payment date
 
Amount
 
   
September 5, 2007
 
100
November 20, 2007
 
150
February 20, 2008
 
150
May 20, 2008
 
150
August 4, 2008
 
90

In addition, in the event that the "research period", as defined in the license agreement, is extended for an additional three year period in accordance with the terms of the license agreement, then the Company is obligated to the following payments to Ramot during the first year of the extended research period:

Payment date
 
Amount
 
   
August 4, 2008
 
60
November 20, 2008
 
150
February 20, 2009
 
170

If the Company fails to make a payment to Ramot on any required payment date, and the Company does not cure the default within seven business days of notice of the default, all claims of Ramot against the Company, which were waived and released by the waiver and release, will be reinstated.

The company paid to Ramot the first three payments total of $400 but has not made yet the last two payments . As a result, the Company is in breach of the new agreement with Ramot and Ramot may terminate the research and license agreement. The Company is negotiating with Ramot to postpone the payments.

As of September 30, 2008 the company’s obligation to Ramot is in the amount of $ 600.

NOTE 5 -
CONSULTING AGREEMENTS

a.
On July 8, 2004, the Company entered into two consulting agreements with Prof. Eldad Melamed and Dr. Daniel Offen (together, the "Consultants"), upon which the Consultants shall provide the Company scientific and medical consulting services in consideration for a monthly payment of $6 each. In addition, the Company granted each of the Consultants, a fully vested warrant to purchase 1,097,215 shares of Common Stock at an exercise price of $0.01 per share. The warrants issued pursuant to the agreement were issued to the Consultants effective as of November 4, 2004. Each of the warrants is exercisable for a seven-year period beginning on November 4, 2005.

b.
As of September 30, 2008, the Company had a total obligation of $190 for services rendered by the Consultants.

10

BRAINSTORM CELL THERAPEUTICS INC. AND SUBSIDIARY
(A development stage company)

NOTE 6 -
SHORT-TERM LOANS

On April 13, 2008, the Company entered into a new agreement with a lender that amended and restated the previous agreement dated September 10,2007 pursuant to which the lender agreed to partially defer and partially convert to the Company’s common stock the payment of $1,250 owed by the Company to the lender based on the payment agreement between the two parties.
Pursuant to the new agreement, the Company agreed to issue 2,857,142 shares of common stock to the lender in lieu of the repayment of $1,000 of the Debt and to pay $250 of the Debt in accordance with the following schedule:

Payment Date
 
Amount
     
May 30, 2008
 
50
July 31, 2008
 
50
September 30, 2008
 
50
December 31, 2008
 
50
February 28, 2009
 
50

The Company paid the May 30, 2008 amounts. The Company has not made the July 31, 2008 and September 30 , 2008 payments.

In addition, on May 13, 2008 the Company issued 2,857,142 shares of common stock to the lender.

The lender agreed that upon payment of the foregoing amounts in accordance with the foregoing schedule and the receipt of the stock grant, all of the Company’s outstanding obligations owed to the lender under the notes will be satisfied in full. The lender also waived any breach or default that may have arisen prior to the date of the new agreement from the failure of the Company to make payments to the lender under any of the past agreements.

Since the outcome of the issuance of the shares was to relieve the debtor from its obligation, based on paragraph 16a of FASB No 140 “accounting for transfer and servicing of financial assets and extinguishment of liabilities “ the company derecognized the liability with the difference recognized in earning.

NOTE 7 -
CAPITAL STOCK

 
a.
The rights of common stock are as follows:

Shares of common stock confer upon their holders the right to receive notice to participate and vote in general meetings of the Company, the right to a share in the excess of assets upon liquidation of the Company and the right to receive dividends, if declared.
 
The common stock of the Company is registered and publicly traded on the Over-the-Counter Bulletin Board service of the National Association of Securities Dealers, Inc. under the symbol BCLI.

11

BRAINSTORM CELL THERAPEUTICS INC. AND SUBSIDIARY
(A development stage company)
 
NOTE 7 -
CAPITAL STOCK (Cont.)
 
b.
Issuance of stocks warrants and options:

1.
Private placements

a)
On June 24, 2004, the Company issued to investors 8,510,000 shares of common stock for total proceeds of $60 (net of $25 issuance expenses).

b)
On February 23, 2005, the Company completed a private placement round for sale of 1,894,808 units for total proceeds of $1,418. Each unit consists of one share of common stock and a three year warrant to purchase one share of common stock at $2.50 per share. This private placement was consummated in four tranches which closed in October 2004, November 2004 and February 2005.

c)
On May 12, 2005, the Company issued to a certain investor 186,875 shares of its common stock for total proceeds of $149 at a price per stock of $0.8.

d)
On July 27, 2005, the Company issued to certain investors 165,000 shares of its common stock for total proceeds of $99 at a price per stock of $0.6.

e)
On August 11, 2005, the Company signed a private placement agreement with investors for the sale of up to 1,250,000 units at a price per unit of $0.8. Each unit consists of one share of common stock and one warrant to purchase one share of common stock at $1.00 per share. The warrants are exercisable for a period of three years from issuance. On March 31, 2005, the Company sold 312,500 units for total net proceeds of $225. On December 7, 2005, the Company sold 187,500 units for total net proceeds of $135.

f)
On July 2, 2007 the Company entered into an investment agreement, pursuant to which the Company agreed to sell up to 27,500,000 shares of the Company's common stock, for an aggregate subscription price of up to $5 million and warrants to purchase up to 30,250,000 shares of common stock. Separate closings of the purchase and sale of the shares and the warrants shall take place as follows:
 
Purchase date
 
Purchase price
 
Number of subscription shares
 
Number of warrant shares
 
               
August 30, 2007
 
$
1,250 (includes $250 that paid as a convertible loan (Note 6c)
 
 
6,875,000
   
7,562,500
 
November 15, 2007
 
$
750
   
4,125,000
   
4,537,500
 
February 15, 2008
 
$
750
   
4,125,000
   
4,537,500
 
May 15, 2008
 
$
750
   
4,125,000
   
4,537,500
 
July 30, 2008
 
$
750
   
4,125,000
   
4,537,500
 
November 15, 2008
 
$
750
   
4,125,000
   
4,537,500
 

12

BRAINSTORM CELL THERAPEUTICS INC. AND SUBSIDIARY
(A development stage company)

NOTE 7 -
CAPITAL STOCK (Cont.)

1.
Private placements (Cont)

f)
(Cont.)

At each closing date, the Company shall deliver to the investor the number of shares and warrants, subject to customary closing conditions and the delivery of funds, described above. The warrants shall have the following exercise prices: (i) the first 10,083,333 warrants will have an exercise price of $0.20 per stock; (ii) the next 10,083,333 warrants will have an exercise price of $0.29 per stock; and (iii) the final 10,083,334 Warrants issued will have an exercise price of $0.36 per stock. All warrants will expire on November 5, 2011.

As of September 30,2008, the investor completed payments of the first four installments and $133 of the fifth installment and the Company issued to the investor and its designee an aggregate of 19,250,000 shares of common stock and a warrant to purchase 10,083,333 shares of the company's common stock at an exercise price of $0.20 per share , a warrant to purchase 10,083,333 shares of common stock at an exercise price of $0.29 per share and a warrant to purchase 1,008,334 shares of common stock at an exercise price of $0.36 per share.The warrants may be exercised at any time and expire on November 5, 2011.
 
In addition, the Company agreed to issue an aggregate of 1,250,000 shares of common stock to a related party as an introduction fee for the investment. The shares shall be issued pro rata to the funds received from the investor.
As of September 30, 2008, 875,000 shares of common stock had been issued as an introduction fee.

2.
Share-based compensation to employees and to directors

a)
Options to employees and directors:

On November 25, 2004, the Company's stockholders approved the 2004 Global Stock Option Plan and the Israeli Appendix thereto (which applies solely to participants who are residents of Israel) and on March 28, 2005, the Company's stockholders approved the 2005 U.S. Stock Option and Incentive Plan, and the reservation of 9,143,462 shares of common stock for issuance in the aggregate under these stock option plans.

Each option granted under the plans is exercisable until the earlier of ten years from the date of grant of the option or the expiration dates of the respective option plans. The 2004 and 2005 options plans will expire on November 25, 2014 and March 28, 2015, respectively. The exercise price of the options granted under the plans may not be less than the nominal value of the shares into which such options are exercised. The options vest primarily over three or four years. Any options that are canceled or forfeited before expiration become available for future grants.

On June 5, 2008, the Company's stockholders approved to amend and restate the Company’s 2004 Global Share Option Plan and 2005 U.S. Stock Option and Incentive Plan to increase the number of shares of common stock available for issuance under these stock option plans in the aggregate by 5,000,000 shares.

As of September 30, 2008, 5,151,684 options are available for future grants.

13

BRAINSTORM CELL THERAPEUTICS INC. AND SUBSIDIARY
(A development stage company)


NOTE 7 -
CAPITAL STOCK (Cont.)
 
2.
Share-based compensation to employees and to directors (Cont.)

a)
(Cont.)

On May 27, 2005, the Company granted to one of its directors an option to purchase 100,000 shares of its common stock, at an exercise price of $0.75. The options are fully vested and are exercisable for a period of 10 years.

On February 6, 2006, the Company entered into an amendment to the Company's option agreement with Mr. David Stolick, the Company's Chief Financial Officer. The amendment changes the exercise price of the 400,000 options granted to him on February 13, 2005 to $0.15 per share from $0.75 per share.

On May 2, 2006, the Company granted to one of its directors an option to purchase 100,000 shares of its common stock, at an exercise price of $0.15. The options are fully vested and are exercisable for a period of 10 years. The compensation related to the options, in the amount of $48,was recorded as general and administrative expenses

On June 22, 2006, the Company entered into an amendment to the Company's option agreement with two of its employees. The amendment changes the exercise price of 270,000 options granted to them to $0.15 per share from $0.75 per share. The excess of the fair value resulting from the modification amounts to $2 is recorded as general and administration expense over the remaining vesting period of the option.

On September 17, 2006, the Company entered into an amendment to the Company's option agreement with one of its directors. The amendment changes the exercise price of 100,000 options granted to them to $0.15 per share from $0.75 per share.

On March 21, 2007, the Company granted to one of its directors an option to purchase 100,000 shares of its common stock, at an exercise price of $0.15. The option is fully vested and is exercisable for a period of 10 years. The compensation related to the options in the amount of $43 was recorded as general and administrative expenses.

On July 1, 2007, the Company granted to one of its directors an option to purchase 100,000 shares of its common stock, at an exercise price of $0.15. The option is fully vested and is exercisable for a period of 10 years. The compensation related to the options in the amount of $38 was recorded as general and administrative expenses. On October 22, 2007, the Company and the director agreed to cancel and relinquish all the options which were granted om July 1 , 2007

On July 16, 2007, the Company granted to one of its directors an option to purchase 100,000 shares of its common stock, at an exercise price of $0.15. The option is fully vested and is exercisable for a period of 10 years. The compensation related to the options in the amount of $75 was recorded as general and administrative expenses.

On August 27, 2007, the Company granted to one of its directors an option to purchase 100,000 shares of its common stock, at an exercise price of $0.15. The option is fully vested and is exercisable for a period of 10 years. The compensation related to the options in the amount of $84 was recorded as general and administrative expenses.


14

BRAINSTORM CELL THERAPEUTICS INC. AND SUBSIDIARY
(A development stage company)

NOTE 7 -
CAPITAL STOCK (Cont.)
 
2.
Share-based compensation to employees and to directors: (Cont.)

a)
(Cont.)

On October 23, 2007, the Company granted to its CEO an option to purchase 1,000,000 shares of Common Stock at an exercise price of $0.87 per share. The option vests with respect to 1/6 of the option on each six month anniversary and expires after 10 years. The total compensation related to the option is $733, which is amortized over the vesting period as general and administrative expense. An amount of $46 was recorded as general and administrative expense.

A summary of the Company's option activity related to options to employees and directors, and related information is as follows:
 
   
Nine months ended
September 30, 2008
 
   
Amount of options
 
Weighted average exercise price
 
        
$
 
           
Outstanding at beginning of the period
   
5,280,760
 
$
0.372
 
Granted
   
170,000
   
0.49
 
Exercised
   
(17,399
)
 
0.15
 
               
Outstanding at end of period
   
5,433,361
 
$
0.377
 
               
Vested and expected-to-vest options at end of the period
   
3,723,127
 
$
0.247
 
               

Compensation expenses recorded by the Company in respect to its stock based employee and directors' compensation award in accordance with SFAS-123(R) for the nine months ended September 30 , 2008, amounted to $478.

b)
Restricted shares to directors:

On May 27, 2005, the Company issued to two of its directors 200,000 restricted shares of common stock (100,000 each). The restricted shares are subject to the Company's right to repurchase them at a purchase price of par value ($0.00005). The restrictions on the shares shall lapse in three annual and equal portions commencing with the grant date.

15

BRAINSTORM CELL THERAPEUTICS INC. AND SUBSIDIARY
(A development stage company)

NOTE 7 -
CAPITAL STOCK (Cont.)

2.
Share-based compensation to employees and to directors (Cont.)

b)
Restricted shares to directors: (Cont.)

On May 2, 2006, the Company issued to two of its directors 200,000 restricted shares of common stock (100,000 each). The restricted shares are subject to the Company's right to repurchase them at a purchase price of par value ($0.00005). The restrictions of the shares shall lapse in three annual and equal portions commencing with the grant date. The compensation related to the stocks issued amounted to $104, which will be amortized over the vesting period as general and administrative expenses.
 
On April 20, 2007, based on a board resolution dated March 21, 2007, the Company issued to its director 100,000 restricted shares of common stock. The restricted shares are subject to the Company's right to repurchase them at a purchase price of par value ($0.00005). The restrictions of the shares shall lapse in three annual and equal portions commencing with the grant date. The compensation related to the shares issued amounted to $47, which will be amortized over the vesting period as general and administrative expenses.
 
In addition, on April 20, 2007, based on a board resolution dated March 21, 2007, the Company issued to another director 100,000 restricted shares of common stock. The restricted shares are not subject to any right to repurchase, and the compensation related to the shares issued amounted to $47 was recorded as prepaid general and administrative expenses in the three months ended March 31, 2007.

On August 27, 2008, the Company issued to its director 960,000 shares of common stock upon a cashless exercise by the director of a warrant to purchase 1,000,000 shares of Common Stock at an exercise price of $.01 per share that was acquired by the director from Ramot.

3.
Stock and warrants to service providers and investors:

The Company accounts for stock option and warrant grants issued to non-employees using the guidance of SFAS No. 123(R), "Accounting for Stock-Based Compensation" and EITF No. 96-18: "Accounting for Equity Instruments that are Issued to Other Than Employees for Acquiring, or in Conjunction with Selling, Goods or Services," whereby the fair value of such option and warrant grants is determined using the Black-Scholes options pricing model at the earlier of the date at which the non-employee's performance is completed or a performance commitment is reached.

16

BRAINSTORM CELL THERAPEUTICS INC. AND SUBSIDIARY
(A development stage company)

NOTE 7 -
CAPITAL STOCK (Cont.)
 
3.
Stock and warrants to service providers and investors: (Cont.)

a)
Warrants:
 
Issuance date  
Number of warrants issued
 
Exercised
 
Forfeited
 
Outstanding
 
Exercise
Price
$
 
Warrants
exercisable
 
Exercisable
through
 
                               
November 2004
   
12,800,845
   
3,141,925
   
40,000
   
9,618,920
   
0.01
   
9,618,920
   
November 2012
 
December 2004
   
1,800,000
   
1,800,000
         
-
   
0.00005
   
--
   
-
 
February 2005
   
1,894,808
         
1,894,808
   
-
   
2.5
   
-
       
May 2005
   
47,500
               
47,500
   
1.62
   
47,500
   
May 2010
 
June 2005
   
30,000
               
30,000
   
0.75
   
30,000
   
June 2010
 
August 2005
   
70,000
         
70,000
   
-
   
0.15
   
-
   
-
 
September 2005
   
3,000
   
3,000
         
-
   
0.15
   
-
   
-
 
September 2005
   
36,000
               
36,000
   
0.75
   
36,000
   
September 2010
 
September-December 2005
   
500,000
         
312,500
   
187,500
   
1
   
187,500
   
December 2008
 
December 2005
   
20,000
   
20,000
         
-
   
0.15
   
-
   
-
 
December 2005
   
457,163
               
457,163
   
0.15
   
419,066
   
July 2010
 
February 2006
   
230,000
               
230,000
   
0.65
   
153,333
   
February 2008
 
February 2006
   
40,000
               
40,000
   
1.5
   
40,000
   
February 2011
 
February 2006
   
8,000
               
8,000
   
0.15
   
8,000
   
February 2011
 
February 2006
   
189,000
   
97,696
   
91,304
   
-
   
0. 5
   
-
   
-
 
May 2006
   
50,000
               
50,000
   
0.0005
   
50,000
   
May 2016
 
May -December 2006
   
48,000
               
48,000
   
0.35
   
48,000
   
May - December 2011
 
May -December 2006
   
48,000
               
48,000
   
0.75
   
48,000
   
May - December 2011
 
May 2006
   
200,000
               
200,000
   
1
   
200,000
   
May 2011
 
June 2006
   
24,000
               
24,000
   
0.15
   
24,000
   
June 2011
 
May 2006
   
19,355
               
19,355
   
0.15
   
19,355
   
May 2011
 
October 2006
   
630,000
   
630,000
         
-
   
0.3
   
-
   
-
 
December 2006
   
200,000
               
200,000
   
0.45
   
200,000
   
December 2008
 
March 2007
   
200,000
               
200,000
   
0.47
   
200,000
   
March 2012
 
March 2007
   
500,000
               
500,000
   
0.47
   
250,000
   
March 2017
 
March 2007
   
50,000
               
50,000
   
0.15
   
50,000
   
March 2010
 
March 2007
   
15,000
               
15,000
   
0.15
   
15,000
   
February 2012
 
February 2007
   
50,000
               
50,000
   
0.45
   
50,000
   
February 2009
 
March 2007
   
225,000
               
225,000
   
0.45
   
225,000
   
March 2009
 
March 2007
   
50,000
               
50,000
   
0.45
   
50,000
   
March 2010
 
April 2007
   
33,300
               
33,300
   
0.45
   
33,300
   
April 2009
 
May 2007
   
250,000
         
250,000
   
-
   
0.45
   
-
   
-
 
July 2007
   
500,000
               
500,000
   
0.39
   
194,444
   
July 2017
 
September 2007
   
500,000
               
500,000
   
0.15
   
500,000
   
August 2017
 
August 2007
   
7,562,500
               
7,562,500
   
0.2
   
7,562,500
   
November 2011
 
July 2007
   
30,000
               
30,000
   
0.45
   
30,000
   
July 2009
 
July 2007
   
100,000
               
100,000
   
0.45
   
100,000
   
July 2010
 
October 2007
   
200,000
               
200,000
   
0.15
   
150,000
   
August - October 2017
 
November 2007
   
2,520,833
               
2,520,833
   
0.20
   
2,520,833
   
November 2011
 
November 2007
   
2,016,667
               
2,016,667
   
0.29
   
2,016,667
   
November 2011
 
April 2008
   
4,537,500
               
4,537,500
   
0.29
   
4,537,500
   
November 2011
 
August 2008
   
3,529,166
               
3,529,166
   
0.29
   
3,529,166
   
November 2011
 
August 2008
   
1,083,333
               
1,083,333
   
0.36
   
1,008,334
   
November 2011
 
     
43,223,970
   
5,692,621
   
2,658,612
   
34,872,737
         
34,152,418
       
 
17

BRAINSTORM CELL THERAPEUTICS INC. AND SUBSIDIARY
(A development stage company)

NOTE 7 -
CAPITAL STOCK (Cont.)
 
3.
Stock and warrants to service providers and investors: (Cont.)

b)
Recent stock developments
 
On February 18, 2008, the Company issued 75,937 shares of the Company’s common stock to an investor pursuant to conversion request of the entire accrued principal and interest amount of a $27 Convertible Promissory Note issued to such investor on April 10, 2007 .

On February 21, 2008, the Company issued 619,523 shares of the Company’s common stock to an investor pursuant to conversion request of the entire accrued principal and interest amount of a $217 Convertible Promissory Note issued to such investor on December 12, 2006.

On May 13, 2008, the Company issued 2,857,142 shares of the Company’s common stock to an investor pursuant to a payments and conversion agreement of the investor’s loans to the company (see note 6).

On May 20, 2008, the Company issued to its finance advisor 90,000 shares of the Company's common stock. The shares are for $35 payable to the finance advisor for introduction fee of past convertible loans. Related compensation in the amount of $36 was recorded as finance expenses.

On June 5, 2008, the Company issued 92,008 shares of the Company’s common stock to an investor pursuant to conversion request of the entire accrued principal and interest amount of a $32 Convertible Promissory Note issued to such investor on July 3, 2007.

18

BRAINSTORM CELL THERAPEUTICS INC. AND SUBSIDIARY
(A development stage company)

NOTE 7 -
CAPITAL STOCK (Cont.)
 
3.
Stock and warrants to service providers and investors: (Cont.)

b)
Recent stock developments
 
A summary of the Company's stock award activity related to shares issued to service providers, and related information is as follows:
 
     
Nine months ended
September 30, 2008
 
     
Amount of shares
   
Weighted average issue price
 
           
$
 
               
Outstanding at beginning of the period
   
2,851,224
   
0.86
 
Issued
   
90,000
   
0.40
 
               
Outstanding at end of the period
   
2,941,224
   
0.85
 

c)
Stock-based compensation recorded by the Company in respect of stock and warrants granted to service providers amounted to $76 for the nine months ended September 30, 2008.

The total stock-based compensation expense, related to shares, options and warrants granted to employees and service providers, was comprised, at each period, as follows:

   
Nine months ended
September 30,
 
Period from September 22, 2000 (inception date) through September 31
 
   
2 0 0 8
 
2 0 0 7
 
2 0 0 8
 
   
Unaudited
     
               
Research and development
   
121
   
513
   
17,338
 
General and administrative
   
397
   
1,504
   
7,471
 
Financial expenses
   
36
   
20
   
56
 
Total stock-based compensation expense
   
554
   
2,037
   
24,865
 

19

BRAINSTORM CELL THERAPEUTICS INC. AND SUBSIDIARY
(A development stage company)

NOTE 8-
SUBSEQUENT EVENTS

a.  
On November 5, 2008, the Company's Board of Directors approved the following resolutions :

1.  
As a result of the current economic situation and the difficulty to raise immediate funds to support all of the Company’s projects, the Board of Directors decided to reduce the Company's activity and focus only on the effort to reach clinical trials in ALS in 2009.

2.  
To amend the exercise price of the option to purchase 1,000,000 shares of common stock granted to the Company’s CEO on October 23, 2007 to $0.15 per share from $0.87 per share.

3.  
To extend the exercise period after termination of the employees current option to purchase shares of common stock to one year.
 
20

 
Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations.
 SPECIAL NOTE REGARDING FORWARD-LOOKING STATEMENTS

This quarterly report contains numerous statements, descriptions, forecasts and projections, regarding Brainstorm Cell Therapeutics Inc. and its potential future business operations and performance. These statements, descriptions, forecasts and projections constitute “forward-looking statements,” and as such involve known and unknown risks, uncertainties, and other factors that may cause our actual results, levels of activity, performance and achievements to be materially different from any results, levels of activity, performance and achievements expressed or implied by any such “forward-looking statements.” Some of these are described under “Risk Factors” in this report and in our annual report on Form 10-KSB for the fiscal year ended December 31, 2007. In some cases you can identify such “forward-looking statements” by the use of words like “may,” “will,” “should,” “could,” “expects,” “hopes,” “anticipates,” “believes,” “intends,” “plans,” “estimates,” “predicts,” “likely,” “potential,” or “continue” or the negative of any of these terms or similar words. These “forward-looking statements” are based on certain assumptions that we have made as of the date hereof. To the extent these assumptions are not valid, the associated “forward-looking statements” and projections will not be correct. Although we believe that the expectations reflected in these “forward-looking statements” are reasonable, we cannot guarantee any future results, levels of activity, performance or achievements. It is routine for our internal projections and expectations to change as the year or each quarter in the year progresses, and therefore it should be clearly understood that the internal projections and beliefs upon which we base our expectations may change prior to the end of each quarter or the year. Although these expectations may change, we may not inform you if they do and we undertake no obligation to do so. We caution investors that our business and financial performance are subject to substantial risks and uncertainties. In evaluating our business, prospective investors should carefully consider the information set forth under the caption “Risk Factors” in addition to the other information set forth herein and elsewhere in our other public filings with the Securities and Exchange Commission.

Company Overview
 
Brainstorm Cell Therapeutics Inc. (“Brainstorm” or the “Company”) is a leading company developing stem cell therapeutic products based on breakthrough technologies enabling the in-vitro differentiation of bone marrow stem cells to neural-like cells. We aim to become a leader in adult stem cell transplantation for neurodegenerative diseases. Our focus is on utilizing the patient’s own bone marrow stem cells to generate neuron-like cells that may provide an effective treatment initially for Parkinson’s Disease (“PD”), Amyotrophic Lateral Sclerosis (“ALS”) and spinal cord injury.

Our core technology was developed through a collaboration between prominent neurologist, Prof. Eldad Melamed, Head of Neurology of the Rabin Medical Center and member of the Scientific Committee of the Michael J. Fox Foundation for Parkinson's Research, and expert cell biologist Dr. Daniel Offen, of the Felsenstein Medical Research Center of Tel Aviv University.

The Company’s team is among the first to demonstrate creation of neurotrophic-factor secreting cells (glial cells) from in-vitro differentiated bone marrow cells that produce neurotrophic factors (“NTF”) including GDNF, BDNF, NGF and IGF-1.
 
The team is also among the first to have successfully demonstrated release of dopamine from in-vitro differentiated bone marrow cells. Moreover, in research conducted by this team, implantation of these differentiated cells into brains of animal models that had been induced to Parkinsonian behavior markedly improved their symptoms.

Our aim is to provide neural stem cell transplants that (i) “replace” damaged dopaminergic nerve cells and diseased tissue by augmentation with healthy dopamine producing cells; and (ii) maintain, preserve and restore the damaged and remaining dopaminergic cells in the patient’s brain, protecting them from further degeneration.
 
21

 
Brainstorm holds exclusive worldwide rights to commercialize the NurOwn(TM) technology, through a licensing agreement with Ramot at Tel Aviv University Ltd. (“Ramot”), the technology transfer company of Tel Aviv University. The agreement also provides for further research, funded by Brainstorm, to be performed by Prof. Melamed, Dr. Offen and members of their research team at the Felsenstein Medical Research Center. The results of this research are licensed to us under the terms of the license agreement.
 
On December 21, 2007, we entered into a Cooperative Research Agreement with Rutgers University. Pursuant to the Cooperative Research Agreement, our subsidiary and Rutgers University will work jointly in researching the use of differentiated stem cells for the treatment of spinal cord injury. This research project began in January and is expected to conclude during 2008.

On April 1, 2008, we started to operate our new animal house and we are conducting new experiments following our work plan.

We are currently in the developmental stage of our technology and products and we are going to begin the process of seeking regulatory approval from regulatory agencies in the U.S., Israel and Europe. Our efforts are directed at the development of the technology from the lab to the clinic with the following main objectives:
 
·  
Developing the cell differentiation process according to Food and Drug Administration (“FDA”) and the European agency for evaluation of medical product (“EMEA”) guidelines;
 
·   
Demonstrating safety and efficacy first in animals and then in human patients; and
 
·   
 Setting up centralized facilities to provide NurOwn(TM) therapeutic products and services for transplantation in patients.
 
As a result of limited cash resources at this time and the faster path through necessary clinical trials, the Company recently determined to focus all of its efforts on ALS, and will for now will not allocate resources towards Parkinson’s Disease. As a result of this new focus and the Company’s limited cash resources, the Company recently significantly downsized its employee-base.

The Company was incorporated under the laws of the State of Washington on September 22, 2000. On July 8, 2004, the Company entered into the licensing agreement with Ramot to acquire certain stem cell technology and decided to discontinue all activities related to the sales of digital data recorder products. On October 25, 2004, the Company opened its wholly-owned subsidiary, Brainstorm Cell Therapeutics Ltd. in Israel. On December 18, 2006, the stockholders of the Company approved a proposal to change the state of incorporation of the Company from the State of Washington to the State of Delaware. The reincorporation was completed on December 21, 2006 through the merger of the Company into a newly formed, wholly-owned Delaware subsidiary of Brainstorm, also named Brainstorm Cell Therapeutics Inc.
 
Results of Operations

The Company has been a development stage company since its inception. For the period from inception (September 22, 2000) until September 30, 2008, the Company has not earned any revenues from operations. The Company does not expect to earn revenues from operations until 2013. In addition, the Company has incurred operating costs and expenses of approximately $2,593,000 during the nine months ending September 30, 2008, and approximately $32,518,000 for the period from inception (September 22, 2000) until September 30, 2008. Operating expenses incurred since inception were approximately $11,488,000 for general and administrative expenses and $21,030,000 for research and development costs.
 
22

 
Research and Development, net:
 
Research and development expenses for the nine months ended September 30, 2008 and 2007 were $1,165,000 and $1,322,000, respectively, which includes stock-based compensation expense in each of the nine month periods. Stock-based compensation decreased by $392,000 to $121,000 for the nine months ended September 30, 2008 from $513,000 for the nine months ended September 30, 2007. In addition, the Company grant from The Office of the Chief Scientist increased by $260,000 to $458,000 for the nine months ended September 30, 2008 from $198,000 for the nine months ended September 30, 2007.
 
Research and development expenses for the three months ended September 30, 2008 and 2007 were $292,000 and $326,000, respectively, which includes stock-based compensation expense in each of the three month periods. Stock-based compensation decreased by $118,000 to $17,000 for the three months ended September 30, 2008 from $135,000 for the three months ended September 30, 2007.

Therefore, although there was a decrease in research and development, net expenses for each of the three and nine month periods ended September 30, 2008 from the research and development expenses, net for each of the three and nine month periods ended September 30, 2007, research and development expenses, excluding stock-based compensation expenses, and participation from The Office of the Chief Scientist have increased. The increase in research and development expenses is primarily due to an increase in salary expenses as we have a greater number of employees and subcontractors due in part to the Cooperative Research Agreement with Rutgers University and in part on an expansion of our research activities, including operating our new animal house.

General and Administrative
 
General and administrative expenses for the nine months ended September 30, 2008 and 2007 were $1,428,000 and $2,070,000, respectively. General and administrative expenses for the nine months ended September 30, 2008 consisted of $397,000 in stock-based compensation expenses and $1,031,000 in salary, legal, audit, public and investor relations and other expenses. General and administrative expenses for the nine months ended September 30, 2007 consisted of $1,504,000 in stock-based compensation expenses and $566,000 in other expenses.

General and administrative expenses for the three months ended September 30, 2008 and 2007 were $405,000 and $865,000, respectively. General and administrative expenses for the three months ended September 30, 2008 consisted of $125,000 in stock-based compensation expenses and $280,000 in salary, legal, audit, public and investor relations and other expenses. General and administrative expenses for the three months ended September 30, 2007 consisted of $638,000 in stock-based compensation expenses and $227,000 in other expenses.

General and administrative expenses, excluding stock-based compensation expenses, have increased primarily due to (i) an increase in salary expenses as we have a greater number of employees and consultants and (ii) an increase in our legal and public relations expenses.
 
Financial Expenses
 
Financial expenses decreased by $677,000 to $253,000 for the nine months ended September 30, 2008 from $930,000 for the nine months ended September 30, 2007. Financial expenses decreased by $235,000 to $31,000 for the three months ended September 30, 2008 from $266,000 for the three months ended September 30, 2007.

The decrease in financial expenses for both the three and nine month period ended September 30, 2008 is primarily attributable to a decrease in amortization of the discount on short-term convertible loans.
 
23

 
Net Loss
 
Net loss for the nine and three months ended September 30, 2008 was $2,846,000 and $728,000, respectively, as compared to a net loss of $4,338,000 and $1,462,000 for the nine and three months ended September 30, 2007. Net loss per share for the nine and three months ended September 30, 2008 was $0.06 and $0.01, respectively, as compared to a net loss per share of $0.16 and $0.05 for the nine and three months ended September 30, 2007. The decrease in the net loss is mainly due to a decrease in stock-based compensation expenses and a decrease in amortization of discount on short-term convertible loans. The weighted average number of shares of common stock used in computing basic and diluted net loss per share for the nine and three months ended September 30, 2008 was 46,958,440, and 51,354,951, respectively, compared to 26,373,349 and 29,868,357 for the nine and three months ended September 30, 2007. This increase was due to (i) the issuance of shares in a private placement, (ii) the conversion of convertible loans, (iii) the exercise of warrants and (iv) the issuance of shares to service providers.
 
Liquidity and Capital Resources
 
The Company has financed its operations since inception primarily through private sales of its common stock and the issuance of convertible promissory notes. At September 30, 2008, we had $148,000 in total current assets and $2,703,000 in total current liabilities.
 
Net cash used in operating activities was $1,589,000 for the nine months ended September 30, 2008. Cash used for operating activities in the nine months ended September 30, 2008 was primarily for payment of salaries and fees to our employees, consultants, subcontractors and services providers and purchase of laboratory materials.
 
Net cash used in investing activities was $158,000 for the nine months ended September 30, 2008. Cash used for investing activities in the nine months ended September 30, 2008 was primarily for building the animal house.
 
Net cash provided by financing activities was $1,682,000 for the nine months ended September 30, 2008 and is primarily attributable to funds received from ACCBT (defined below) under the Subscription Agreement (defined below).
 
We have a licensing agreement with Ramot under which we owe approximately $95,000 per quarter. In addition, we have an agreement with a lender under which we must pay $30,000 over the next three months.
 
Our other material cash needs for the next 12 months will include payment of employee salaries, payments for clinical trials in ALS and animal experiments, lease payments, payments to Ramot, payments with respect to patents, payment of construction fees for facilities to be used in our research and development, payment of fees to our consultants and legal advisors and capital equipment expenses.

On July 2, 2007, we entered into a subscription agreement (the “Subscription Agreement”) with ACCBT Corp. (“ACCBT”), pursuant to which we agreed to sell and issue (i) up to 27,500,000 shares of our common stock for an aggregate subscription price of up to $5.0 million, and (ii) for no additional consideration, warrants to purchase up to 30,250,000 shares of our common stock. Subject to certain closing conditions, separate closings of the purchase and sale of the shares and the warrants are scheduled to take place from August 30, 2007 through November 15, 2008. To date, we have received an aggregate of $3.7 million from ACCBT.
 
24

 
We will need to raise substantial additional capital in order to meet our anticipated expenses. If we are not able to raise substantial additional capital, we may not be able to continue to function as a going concern and we may have to cease operations. Even if we obtain funding sufficient to continue functioning as a going concern, we will be required to raise a substantial amount of capital in the future in order to reach profitability and to complete the commercialization of our products. Our ability to fund these future capital requirements will depend on many factors, including the following:

·  
our ability to obtain funding from third parties, including any future collaborative partners;

·  
the scope, rate of progress and cost of our clinical trials and other research and development programs;

·  
the time and costs required to gain regulatory approvals;

·  
the terms and timing of any collaborative, licensing and other arrangements that we may establish;

·  
the costs of filing, prosecuting, defending and enforcing patents, patent applications, patent claims, trademarks and other intellectual property rights;

·  
the effect of competition and market developments; and

·  
Future pre-clinical and clinical trial results.
 
Critical Accounting Policies 

Our discussion and analysis of our financial condition and results of operations are based on our financial statements, which have been prepared in accordance with accounting principles generally accepted in the U.S. The preparation of these financial statements requires us to make judgments, estimates, and assumptions that affect the reported amounts of assets and liabilities and the disclosure of contingent assets and liabilities at the date of the financial statements as well as the reported revenue and expenses during the reporting periods. We continually evaluate our judgments, estimates and assumptions. We base our estimates on the terms of underlying agreements, our expected course of development, historical experience and other factors we believe are reasonable based on the circumstances, the results of which form our management’s basis for making judgments about the carrying value of assets and liabilities that are not readily apparent from other sources. Actual results may differ from these estimates.

There were no significant changes to our critical accounting policies during the quarter ended September 30, 2008. For information about critical accounting policies, see the discussion of critical accounting policies in our Annual Report on Form 10-KSB for the fiscal year ended December 31, 2007.

Off Balance Sheet Arrangements

We have no off balance sheet arrangements that have or are reasonably likely to have a current or future material effect on our financial condition, changes in financial condition, revenues or expenses, results of operations, liquidity, capital expenditures, or capital resources.
  
Item 3. Quantitative and Qualitative Disclosures About Market Risk.

This information has been omitted as the Company qualifies as a smaller reporting company.
 
25


Item 4T. Controls and Procedures.

Evaluation of Disclosure Controls and Procedures 
 
As of the end of the period covered by this report, we carried out an evaluation, under the supervision and with the participation of our Chief Executive Officer and Chief Financial Officer, of the effectiveness of our disclosure controls and procedures (as defined in Rules 13a-15(e) and 15d-15(e) under the Securities Exchange Act of 1934, as amended (the “Exchange Act”)). Based on this evaluation, our Chief Executive Officer and Chief Financial Officer concluded that, as a result of the material weakness in our internal control over financial reporting described below, our disclosure controls and procedures were not effective, as of the end of the period covered by this report, to ensure that information required to be disclosed by us in the reports we file under the Exchange Act is recorded, processed, summarized and reported within the time periods specified in the Securities and Exchange Commission's rules and forms, and that the information required to be disclosed by us in such reports is accumulated and communicated to our management, including our Chief Executive Officer and Chief Financial Officer, as appropriate to allow timely decisions regarding required disclosure.
 
Internal Control Over Financial Reporting
 
Management identified the following material weakness in its assessment of the effectiveness of internal control over financial reporting as of December 31, 2007, which continued to exist as of September 30, 2008:
 
 
·  
The Company did not maintain effective controls over certain aspects of the financial reporting process because we lacked a sufficient complement of personnel with a level of accounting expertise and an adequate supervisory review structure that is commensurate with the Company’s financial reporting requirements. Specifically, our Chief Financial Officer handles certain accounting issues of the Company alone as there is no one in our accounting and finance departments who is qualified to assist him.
 
Nevertheless, based on a number of factors, including the performance of additional procedures performed by management designed to ensure the reliability of our financial reporting, our Chief Executive Officer and Chief Financial Officer believe that the consolidated financial statements included with this Quarterly Report on Form 10-Q fairly present, in all material respects, our financial position, results of operations, and cash flows as of the dates, and for the periods, presented, in conformity with U.S. GAAP.

Management’s Remediation Initiatives
 
We plan to develop policies and procedures for training of personnel or external advisers to verify that we have a sufficient number of personnel with knowledge, experience and training in the application of generally accepted accounting principles commensurate with our financial reporting and U.S. GAAP requirements. Where necessary, we will supplement personnel with qualified external advisors. Additionally, where appropriate, we plan to identify training on accounting principles and procedures that would benefit our accounting and finance personnel.
 
Changes in Internal Control Over Financial Reporting

Other than as described above, no changes in our internal controls over financial reporting were identified during the quarter ended September 30, 2008 that materially affected, or are reasonably likely to materially affect, such internal control over financial reporting other than those remedial actions disclosed above.
 
26


PART II: OTHER INFORMATION

Item 1. Legal Proceedings.

On April 17, 2008, Chapman, Spira & Carson, LLC (“CSC”), filed a breach of contract complaint in the Supreme Court of the State of New York (the “Court”) against the Company. The complaint alleges that CSC performed its obligations to the Company under a consulting agreement entered into between the parties and that the Company failed to provide CSC with the compensation outlined in the consulting agreement. The complaint seeks compensatory damages in an amount up to approximately $896,667, as well as costs and attorneys’ fees. On June 5, 2008, the Company filed an answer with the Court. We intend to vigorously defend our actions. We cannot predict the scope, timing or outcome of this matter. We cannot predict what impact, if any, this matter may have on our business, financial condition, results of operations and cash flow.
 
Item 1A. Risk Factors.
 
In addition to the other information set forth in this Quarterly Report on Form 10-Q, you should carefully consider the risk factor discussed below and the risk factors previously disclosed in the “Risk Factors” section of our Annual Report on Form 10-KSB for the fiscal year ended December 31, 2007, which could materially affect our business, financial condition or future results, and in our Quarterly Reports on Form 10-Q filed for the current fiscal year. The risks described below and in our Annual Report on Form 10-KSB for the fiscal year ended December 31, 2007 and in our subsequent Quarterly Reports on Form 10-Q are not the only risks we face. Additional risks and uncertainties not currently known to us or that we currently deem to be immaterial also may materially adversely affect our business, financial condition and/or operating results. Other than with respect to the risk factor below, there have been no material changes from the risk factors disclosed in our Annual Report on Form 10-KSB for the fiscal year ended December 31, 2007 or in our Quarterly Reports on Form 10-Q filed for the current fiscal year. The risk factor below was disclosed in our Annual Report on Form 10-KSB and is being updated as set forth below.

Our business in the foreseeable future will be based on technology licensed from Ramot and if this license were to be terminated for any reason, including failure to pay the required research funding or royalties, we would need to change our business strategy and we may be forced to cease our operations. We entered into a Second Amended and Restated Research and License Agreement with Ramot on July 31, 2007 (the “Amended Agreement”). The Amended Agreement imposes on us development and commercialization obligations, milestone and royalty payment obligations and other obligations.

On August 1, 2007, we obtained a waiver and release from Ramot pursuant to which Ramot agreed to an amended payment schedule regarding our payment obligations under the Amended Agreement and waived all claims against us resulting from our previous breaches and non-payment under the original license agreement. The payments described in the waiver and release cover all of our payment obligations (including interest) that were past due and not yet due pursuant to the original license agreement. To date, we have not yet made the May 2008 payment of $150,000 or the August 2008 payment of $90,000 to Ramot We are negotiating an agreement with Ramot to postpone such payments. If we fail to negotiate an agreement with Ramot or if we fail to pay the amounts owed to Ramot in accordance with the new payment schedule, Ramot may have the right to terminate the license and all claims waived by Ramot pursuant to the August 2007 waiver and release may be reinstated. If Ramot elects to terminate our license, we would need to change our business strategy and we may be forced to cease our operations.

In order to execute our business plan, we will need to raise additional capital. If we are unable to raise additional capital on favorable terms and in a timely manner, we will not be able to execute our business plan and we could be forced to restrict or cease our operations. We will need to raise additional funds to meet our anticipated expenses so that we can execute our business plan. We expect to incur substantial and increasing net losses for the foreseeable future as we increase our spending to execute our development programs. Our auditors have expressed in their audit report that there is substantial doubt regarding our ability to continue as a going concern.
 
27


Pursuant to the subscription agreement with ACCBT, we expect to issue and sell additional shares and warrants to ACCBT through November 2008 for aggregate consideration of up to $5,000,000. However, if we do not satisfy the closing conditions contained in the subscription agreement, and if ACCBT does not elect to purchase additional shares and warrants, we will need to seek additional financings to allow us to execute our business plan. Even if ACCBT purchases all of the shares and warrants under the subscription agreement, we will still need to secure additional funds to effect our plan of operations. Recent funding installments (due July 2008) from ACCBT have not been made when expected and we continue to be in need of raising additional cash. We may not be able to raise additional funds on favorable terms, or at all. If we are unable to obtain additional funds on favorable terms and in a timely fashion, we will be unable to execute our business plan and we will be forced to restrict or cease our operations.
 
Assuming we raise additional funds through the issuance of equity, equity-related or debt securities, these securities may have rights, preferences or privileges (including registrations rights) senior to those of the rights of our common stock and our stockholders will experience additional dilution.

Disruption in financial and currency markets could have a negative effect on our business. As has been widely reported, financial markets in the U.S., Europe, Asia and elsewhere have been experiencing extreme disruption in recent months, including, among other things, extreme volatility in security prices, severely diminished liquidity and credit availability, rating downgrades of certain investments and declining valuations of others. Governments have taken unprecedented actions intended to address extreme market conditions that include severely restricted credit and declines in real estate values. While currently these conditions have not impaired our ability to operate our business, there can be no assurance that there will not be a further deterioration in financial markets and confidence in major economies, which can then lead to challenges in the operation of our business. These economic developments affect businesses such as ours in a number of ways, including our ability to obtain the financing that is necessary to continue operating our business. We are unable to predict the likely duration and severity of the current disruption in financial markets and adverse economic conditions and the effects they will have on our business and financial condition.
 
Item 5. Other Information.

During the quarter ended September 30, 2008, we made no material changes to the procedures by which stockholders may recommend nominees to our Board of Directors, as described in our most recent proxy statement.
 
Item 6. Exhibits.

The Exhibits listed in the Exhibit Index immediately preceding such Exhibits are filed with or incorporated by reference in this report.

28

 
SIGNATURES
 
Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.
 
 
 
 
 
 
BRAINSTORM CELL THERAPEUTICS INC.
 
 
 
 
 
 
 
 
November 19, 2008
By:  
/s/ Rami Efrati
 
 
Name: Rami Efrati 
Title: Chief Executive Officer
(Principal Executive Officer)
 
 
 
 
 
 
November 19, 2008
By:  
/s/ David Stolick
 
 
Name: David Stolick
Title: Chief Financial Officer
(Principal Financial and Accounting Officer)
 
 

29

 
EXHIBIT INDEX  

Exhibit
Number
 
Description
31.1
 
Certification of the Principal Executive Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.
 
 
 
31.2
 
Certification of the Principal Financial Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.
 
 
 
32.1
 
Certification of the Principal Executive Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.
 
 
 
32.2
 
Certification of the Principal Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.
 
30