UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, DC 20549
 
Commission File Number: 001-09727

CUSIP Number: 70322H106

FORM 12b-25
 
NOTIFICATION OF LATE FILING
 
(Check One): x Form 10-K and Form 10-KSB o Form 20-F o Form 11-K
 
    o Form 10-Q and Form 10-QSB o Form N-SAR
 
For Period Ended: December 31, 2007
 
o Transition Report on Form 10-K  o Transition Report on Form 10-Q
o Transition Report on Form 20-F       o Transition Report on Form N-SAR
o Transition Report on Form 11-K
 
For the Transition Period Ended :________________________
 
Read attached instruction sheet before preparing form. Please print or type.
 
Nothing in this form shall be construed to imply that the Commission has verified any information contained herein. 
 
If the notification related to a portion of the filing checked above, identify the item(s) to which the notification relates:
 
__________________________________________________________________
 

PART I
REGISTRANT INFORMATION
 
Full name of registrant:    Patient Safety Technologies, Inc.
 
Former name if applicable: ___________________________________________
 
Address of principal executive office (street and number): 43460 Ridge Park Drive, Suite 140
 
City, state and zip code:   Temecula, California 92590

PART II
RULE 12b-25 (b) and (c)
 
If the subject report could not be filed without unreasonable effort or expense and the registrant seeks relief pursuant to Rule 12b-25(b), the following should be completed. (Check box if appropriate.) 
 
x
  
(a)
 The reasons described in reasonable detail in Part III of this form could not be eliminated without unreasonable effort or expense.
       
x
  
(b)
The subject annual report, semi-annual report, transition report on Form 10-K, 20-F, 11-K or Form N-SAR, or portion thereof will be filed on or before the fifteenth calendar day following the prescribed due date; or the subject quarterly report or transition report on Form 10-Q or portion thereof will be filed on or before the fifth calendar day following the prescribed due date; and
 
 
(c)
The accountant’s statement or other exhibit required by Rule 12b-25(c)has been attached if applicable.
 
PART III
NARRATIVE
 
State below in reasonable detail the reasons why Form 10-K, 11-K, 20-F, 10-Q, N-SAR or the transition report portion thereof could not be filed within the prescribed time period.
 
The Company’s Annual Report on Form 10-K for the year ended December 31, 2007 cannot be filed within the prescribed time period because the Company requires additional time for compilation and review to insure adequate disclosure of certain information required to be included in the Form 10-K. The Company’s Annual Report on Form 10-K will be filed on or before the 15th calendar day following the prescribed due date.
 
 
PART IV
OTHER INFORMATION
 
 
(1)
Name and telephone number of person to contact in regard to this notification:

   
William B. Horne, Chief Executive Officer, (951) 587-6201

 
(2)
Have all other periodic reports required under Section 13 or 15(d) of the Securities Exchange Act of 1934 or Section 30 of the Investment Company Act of 1940 during the preceding 12 months or for such shorter period that the registrant was required to file such report(s) been filed? If the answer is no, identify report(s)
 
x Yes o No
 
 
(3)
Is it anticipated that any significant change in results of operations from the corresponding period for the last fiscal year will be reflected by the earnings statements to be included in the subject report or portion thereof?
 
x Yes o No
       
If so, attach an explanation of the anticipated change, both narratively and quantitatively, and, if appropriate, state the reason why a reasonable estimate of the results cannot be made.
 
Patient Safety Technologies, Inc. (the “Company”) anticipates that its revenue for the year ended December 31, 2007 will significantly exceed its revenue for the year ended December 31, 2006. Increases in revenues from sales of its Safety Sponge during the year ended December 31, 2007 reflect an entire year of sales as opposed to the year ended December 31, 2006 in which the Company initially began recognizing revenues from its Safety Sponge late during the quarter ended September 30, 2006. The Company anticipates that its operating expenses and net loss for the year ended December 31, 2007 are significantly less than the expenses and net loss for the year ended December 31, 2006. The decrease in operating expenses for the year ended December 31, 2007 when compared to December 31, 2006, was primarily the result of stock based compensation expenses, amortization of debt discount and to a lesser extent salaries and employee benefits, and interest expense. Net loss decreased for the year ended December 31, 2007 compared to the year ended December 31, 2006 primarily as a result of a significant decrease in operating expenses.

A reasonable estimate of the results cannot be made at this time due to the fact that the compilation, dissemination and review of the information required to be presented in the Form 10-K has not been completed.
 
__________________________________________________________________
 
 
                                     Patient Safety Technologies, Inc.                                             
(Name of Registrant as specified in Charter)
 
has caused this notification to be signed on its behalf by the undersigned thereunto duly authorized.
 
     
Date: March 31, 2008 By:   /s/ William B. Horne
 
William B. Horne
 
Chief Executive Officer