Berlin, Germany, October 23, 2024 (EZ Newswire) -- Clue, a leading menstrual and reproductive health tracking app, today announced the results of the largest study to date, examining the relationship between gastrointestinal (GI) symptoms, mood, and the menstrual cycle. Led by researchers at Johns Hopkins University, the new study provides important insights into the complex link between GI and mood symptoms across the menstrual cycle, particularly for individuals with premenstrual syndrome (PMS).
The study analyzed data from more than 33,000 menstrual cycles over a four year period, across more than 32,000 participants, making it the most comprehensive study of its kind. Participants used Clue’s menstrual tracking app to identify and track their symptoms and opted-in to share their data anonymously for research.
Key findings:
- GI symptoms such as bloating, constipation, diarrhea, and nausea were more frequently tracked in the days leading up to menstruation as compared to the days following it, with a stronger effect observed in those with PMS.
- A strong positive association was found between mood symptoms and GI symptoms across all phases of the menstrual cycle, for both PMS and non-PMS groups, indicating that these symptoms often occur together.
- Participants with self-reported PMS tracked more GI symptoms throughout their entire menstrual cycle compared to those without PMS.
"At Clue, we're committed to advancing society’s understanding of menstrual health through data-driven research. These findings not only validate the experiences of millions of women and people with cycles, but also pave the way for more effective support and treatment during especially difficult times of their menstrual cycles,” said Amanda Shea, Fractional Chief Science Officer at Clue.
With the Clue app, members can track when they feel bloated or gassy, monitor constipation or diarrhea, and log mood fluctuations throughout their cycle. By customizing additional tags, members can capture their unique experiences, and get a clear overview of how gastrointestinal symptoms and mood changes interact during their cycles.
"Reporting your experiences and discomforts to your healthcare provider from memory alone often doesn't reflect the true condition of your health and might not be the most reliable. We recommend tracking both your digestion and feelings daily, and over a longer period, to help you and your healthcare provider analyze cycle-related patterns,” said Shea.
"This study was exciting because it drew from such a large dataset of menstrual cycles, to give a representative look at GI symptoms and mood across the cycle. We were able to see a clear relationship between GI symptoms and mood at multiple points in the menstrual cycle. Previous studies have found links between GI symptoms and mood in people with major depression, but this had not been assessed in the context of the menstrual cycle or premenstrual mood symptoms. We hope this study leads to more research on the gut-brain axis in the context of menstrual health," said Liisa Hantsoo, Ph.D., Assistant Professor in Psychiatry and Behavioral Sciences at the Johns Hopkins School of Medicine and Director of Research in the Johns Hopkins Reproductive Mental Health Center.
The full study can be found here.
About Clue
Clue is the top women-led menstrual and reproductive health app, loved by over 10 million users around the world. With a science-driven approach, Clue enables members to create a powerful personal health record that uses each cycle as a tool to uncover insight into their overall health. From general cycle health education to fertility, pregnancy, menopausal stages, and all changes and choices in between, the Clue app is CE-marked as a Class 1 medical-grade device. Clue regularly partners with researchers from top institutions and universities to help close the data gap and move female health forward. Based in Berlin, Germany, Clue data is protected by the world's strictest data laws (the EU's GDPR) and by Clue's absolute commitment to standing up for the privacy of its users, no matter where they are. For more, visit helloclue.com.
Media Contact
Kirsten Underwood
213-371-2420
kirsten.underwood.ext@helloclue.com
###
