CHLA faculty will share new findings on leukemia, thalassemia, and hemophilia at the world’s largest hematology event

Children’s Hospital Los Angeles faculty will present their latest research on pediatric blood cancers and diseases at the 66th American Society of Hematology (ASH) Annual Meeting and Exposition in San Diego.

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Children’s Hospital Los Angeles faculty will present their latest research on pediatric blood cancers and diseases at the 66th American Society of Hematology (ASH) Annual Meeting and Exposition in San Diego. (Photo: Business Wire)

The annual conference—billed as the world’s largest and most comprehensive hematology event—will take place Dec. 7-10. In 2023, ASH attracted more than 32,000 attendees from over 100 countries.

This year, CHLA faculty will present new research on leukemia, thalassemia, and hemophilia. One of the presentations, led by Sibgha Zaheer, MD, MPH, Medical Director of the Thrombosis Program at CHLA, was selected for the prestigious 2025 Highlights of ASH meetings, which feature the most influential research from the ASH Annual Meeting.

Children’s Hospital Los Angeles is home to the largest pediatric hematology-oncology program in the United States and is ranked No. 6 in the nation for pediatric cancer care by U.S. News & World Report. Here is a day-by-day schedule of CHLA faculty presentations for ASH 2024:

Saturday, Dec. 7, 2024

Sibgha Zaheer, MD, MPH

Selected for the 2025 Highlights of ASH meetings:

• Assessment of the Combined Effects of Emicizumab and Fitusiran with in Vitro Spiking of Simulated Fitusiran (using anti-thrombin antibody) into Plasma From Hemophilia A Patients on Emicizumab- Opens in a new window

Alexandra Kovach, MD

• Monocytic Differentiation in B-Lymphoblastic Leukemia With CRLF2 Rearrangement at Diagnosis: Implications for Pathogenesis and Post-Therapeutic Lineage Switch- Opens in a new window

Sunday, Dec. 8, 2024

Etan Orgel, MD, MS

• Utility of a Second Interim Maintenance Phase to Improve Outcomes for Pediatric Acute Lymphoblastic Leukemia: A Report from the Children’s Oncology Group- Opens in a new window
• Trial in Progress: Update on the TACL T2020-003 Randomized Phase 2 Trial to Improve Diet and Exercise in Acute Lymphoblastic Leukemia (IDEAL-2)- Opens in a new window

Guy Young, MD

• FVIII Exposure Analysis from the HAVEN 7 Study of Emicizumab in Infants with Severe Hemophilia A- Opens in a new window

Monday, Dec. 9, 2024

Christopher Denton, MD

• Myocardial Fibrosis Occurs in Young Non-Transfusion-Dependent Alpha-Thalassemia Intermedia Patients and Is Related to Anemia and Age in Thalassemia- Opens in a new window

Learn more about the Cancer and Blood Disease Institute at CHLA

About Children’s Hospital Los Angeles

Founded in 1901, Children’s Hospital Los Angeles is at the forefront of pediatric medicine and is the largest provider of hospital care for children in California. Children’s Hospital is home to renowned experts who work together across disciplines to deliver inclusive and compassionate care, and drive advances that set pediatric standards across the nation and around the globe. Children’s Hospital Los Angeles provides a level of care to its diverse population of children that is among the best in the world. The hospital is consistently ranked in the top 10 in the nation on U.S. News & World Report’s Honor Roll of Best Children’s Hospitals. CHLA is the top-ranked children’s hospital in California and the Pacific U.S. region for 2024-25. Children’s Hospital Los Angeles embraces its mission to create hope and build healthier futures. Children’s Hospital Los Angeles is among the top 10 children’s hospitals for National Institutes of Health funding. The Saban Research Institute of Children's Hospital Los Angeles supports the full continuum of research, allowing physicians and scientists to translate discoveries into treatments and bring answers to families faster. The pediatric academic medical center also is home to one of the largest training programs for pediatricians in the United States. And the hospital’s commitment to building strong communities is evident in CHLA’s efforts to fight food insecurity, enhance health education and literacy, and introduce more people to careers in health care. To learn more, follow CHLA on Facebook, Instagram, LinkedIn, YouTube, and X, formerly known as Twitter, and visit CHLA.org/blog.

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